Description
SIGNATRET MICROSPHERE 0.05% GEL is an advanced topical dermatological treatment that features Microsphere technology for sustained release of Tretinoin 0.05%, a powerful retinoid derived from Vitamin A. Tretinoin works by increasing skin cell turnover, unclogging pores, and promoting the formation of new, smoother skin.
The microsphere formulation provides gradual release, allowing for better tolerability with minimal skin irritation—making it ideal for long-term use in the treatment of moderate to severe acne vulgaris, textural irregularities, and early signs of aging such as fine lines, wrinkles, and sun damage.
Manufactured and exported globally by Bluepill Express, a trusted third-party pharmaceutical manufacturer and supplier, this gel meets the quality expectations of dermatologists, hospitals, clinics, and cosmetic distributors across regulated and semi-regulated markets.
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Treats acne by reducing inflammation and preventing pore blockages
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Enhances collagen production and skin renewal
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Minimizes fine lines, rough skin texture, and discoloration
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Reduces hyperpigmentation and photodamage
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Controlled release reduces the potential for irritation or peeling
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Acne vulgaris (whiteheads, blackheads, papules, pustules)
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Fine lines and wrinkles
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Skin texture irregularities
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Photodamaged skin (sun spots, pigmentation)
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Post-acne marks and blemishes
SIGNATRET MICROSPHERE GEL delivers Tretinoin in microencapsulated form, ensuring sustained action on the skin. It promotes cellular turnover, unclogs follicles, and helps skin regenerate faster. The microspheres allow for slower absorption, making the treatment more tolerable for sensitive skin.
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Apply once daily, preferably at night
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Cleanse and dry the affected area before application
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Use a pea-sized amount for the entire face
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Avoid excessive sun exposure and use sunscreen during the day
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Do not apply on broken or eczematous skin
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For external use only
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Avoid contact with eyes, mouth, and mucous membranes
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Mild redness, dryness, or peeling may occur during early use
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Not recommended during pregnancy or breastfeeding
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Discontinue use if severe irritation or allergic reaction occurs
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Manufactured by Bluepill Express, a globally trusted name in third-party pharmaceutical production and export
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High-quality formulation with microsphere technology for optimal efficacy and minimal irritation
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Compliant with WHO-GMP, ISO, and global regulatory standards
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Available for bulk export, private labeling, and contract manufacturing
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Trusted by dermatologists, cosmetologists, and skincare professionals worldwide
Bluepill Express serves clients in North America, Latin America, Europe, Africa, CIS, and Asia, offering export-ready packaging and regulatory support for international partners.
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Store in a cool, dry place, below 25°C
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Keep away from direct sunlight
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Do not freeze
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Keep out of reach of children
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Mild irritation, redness, dryness, or peeling
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Temporary worsening of acne may occur initially
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Photosensitivity (use sun protection)
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Rare allergic reactions (discontinue if symptoms persist)
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