Description

METATILE 3 TABLET is a fixed-dose combination tablet designed to manage Type 2 Diabetes Mellitus in adult patients. It integrates three well-established anti-diabetic agents—Glimepiride, Pioglitazone, and Metformin—that work synergistically to regulate blood glucose levels by addressing insulin resistance, stimulating insulin secretion, and decreasing hepatic glucose production.

1. Glimepiride: A sulfonylurea that stimulates pancreatic beta cells to produce insulin. It is fast-acting and long-lasting, helping to lower blood sugar effectively, especially after meals.

2. Pioglitazone: A thiazolidinedione that enhances insulin sensitivity in muscle and adipose tissue. It improves glucose uptake without increasing insulin levels.

3. Metformin: A biguanide that reduces hepatic glucose output and increases peripheral glucose uptake, thereby lowering both fasting and postprandial blood glucose levels.

The combination of these three agents in a single tablet offers comprehensive blood sugar control and is especially beneficial for patients requiring escalation from dual to triple therapy.

• Management of Type 2 Diabetes Mellitus in adults

• For patients inadequately controlled on dual therapy (Metformin + Glimepiride or Pioglitazone)

• To improve insulin sensitivity, reduce insulin resistance, and optimize pancreatic insulin secretion

• Multi-mechanism approach for superior glycemic control

• Reduces fasting and postprandial blood glucose levels

• Minimizes risk of diabetes-related complications

• Convenient once-daily dosage

• Manufactured by Bluepill Express, ensuring international quality and regulatory compliance

• Typically taken once daily with meals, as directed by a physician

• Dosage may vary based on blood glucose levels and clinical condition

• Regular monitoring of blood sugar, liver function, and kidney function is recommended

• Not recommended for Type 1 diabetes or diabetic ketoacidosis

• Use with caution in patients with renal or hepatic impairment

• Risk of hypoglycemia when used with other anti-diabetic agents or missed meals

• May cause weight gain due to pioglitazone

• Contraindicated in heart failure, bladder cancer, and severe kidney dysfunction

• Hypoglycemia

• Nausea, diarrhea

• Weight gain

• Headache

• Edema

• Muscle pain or fatigue

Patients should promptly report any signs of lactic acidosis, urinary discomfort, or jaundice.

Bluepill Express is a globally recognized third-party pharmaceutical manufacturer with certifications including WHO-GMP, ISO, and other international accreditations. With a robust export network across 140+ countries, Bluepill Express ensures the delivery of high-quality, cost-effective medications with complete documentation support, including COA, MSDS, and stability data.

The company specializes in custom formulations, bulk orders, and regulatory-compliant packaging, making it a trusted partner for pharmacies, hospitals, and distributors worldwide.