Description

CLOCHISIGN TAB is an oral anti-inflammatory medication containing Colchicine, primarily used in the treatment and prevention of acute gout flares and familial Mediterranean fever (FMF). Colchicine works by reducing inflammation caused by uric acid crystal deposition in joints and tissues.

Therapeutic Uses:

• Treatment of acute gouty arthritis

• Prevention of recurrent gout attacks

• Management of familial Mediterranean fever (FMF)

• Occasionally used in pericarditis and Behçet’s disease (as per physician guidance)

Mechanism of Action:
Colchicine disrupts the cytoskeletal functions of inflammatory cells, particularly neutrophils, thereby reducing inflammation, pain, and swelling during gout flares. It does not lower uric acid levels but helps control acute symptoms and prevent flare-ups.

Dosage is typically initiated at the first sign of a gout attack and adjusted based on renal function, age, and tolerability. It must be used cautiously in patients with kidney or liver impairment, and under medical supervision to avoid toxicity.

Manufactured under WHO-GMP and ISO-certified standards, CLOCHISIGN TAB is represented globally by BLUEPILL EXPRESS, a trusted exporter of pharmaceutical formulations. With supply operations across Asia, Africa, Europe, the Middle East, and the Americas, BLUEPILL EXPRESS ensures quality compliance, export readiness, and reliable delivery worldwide.