Description

SIGBAN 150 SR TABLET is a high-quality, sustained-release formulation of Bupropion Hydrochloride 150 mg, developed for the management of major depressive disorder (MDD) and as an aid to smoking cessation. As a norepinephrine-dopamine reuptake inhibitor (NDRI), Bupropion works by enhancing the levels of these neurotransmitters in the brain, helping improve mood, motivation, and focus.

This dual-action therapy is widely recognized for its effectiveness in managing depressive symptoms and nicotine cravings, offering a stimulant-like effect without being habit-forming. SIGBAN 150 SR is particularly useful for patients who are intolerant to or do not respond well to selective serotonin reuptake inhibitors (SSRIs).

Manufactured by Bluepill Express, SIGBAN 150 SR is produced in internationally certified facilities adhering to WHO-GMP, ISO, and other regulatory standards, making it suitable for global distribution across regulated and semi-regulated markets.

• Major Depressive Disorder (MDD)

• Smoking Cessation Support (as part of a structured quit program)

• Off-label: Seasonal Affective Disorder (SAD), ADHD (under supervision)

Bupropion inhibits the reuptake of norepinephrine and dopamine, two key neurotransmitters involved in mood regulation and addiction pathways. Unlike traditional antidepressants, it does not significantly affect serotonin levels, minimizing common side effects such as weight gain and sexual dysfunction.

In smoking cessation, it reduces cravings and withdrawal symptoms by modulating brain reward circuits associated with nicotine addiction.

• Typical dosage: One tablet (150 mg) once or twice daily, depending on therapeutic indication

• Tablets should be swallowed whole and not crushed or chewed

• Dosing should start at 150 mg once daily and may increase to twice daily after 3 days, as per clinical assessment

• Full effect in depression may take 2–4 weeks, while smoking cessation support begins within 7–14 days

• Sustained-release formula for stable blood levels and once/twice daily dosing

• Non-sedating and weight-neutral profile

• Effective for mood enhancement and addiction management

• Minimal sexual side effects compared to SSRIs

• Trusted and consistent supply by Bluepill Express for global B2B markets

• Contraindicated in patients with a history of seizure disorders

• Not recommended for patients with bulimia or anorexia nervosa

• Caution in patients with liver impairment, hypertension, or bipolar disorder

• Should not be used with other forms of bupropion or monoamine oxidase inhibitors (MAOIs)

• Monitor for signs of agitation, mood swings, or suicidal ideation

• Dry mouth

• Insomnia

• Headache

• Dizziness

• Increased sweating

• Anxiety or restlessness in early therapy

• Seizures (rare; dose-dependent risk)

Bluepill Express is a trusted global pharmaceutical exporter offering third-party manufacturing services with unmatched quality assurance. Our products like SIGBAN 150 SR TABLET are manufactured in world-class, certified facilities with end-to-end supply chain support for hospitals, clinics, distributors, and pharmacy chains worldwide.

• Custom labeling and international branding

• Regulatory documents and COAs for international registration

• Consistent stock availability for high-demand therapies

• Flexible export volumes for both large and small-scale buyers