Description
TRAZOSIG 100 TABLET is a prescription medication formulated with Trazodone Hydrochloride 100 mg, a serotonin antagonist and reuptake inhibitor (SARI) used in the management of major depressive disorder (MDD), generalized anxiety, and chronic insomnia. Trazodone is widely prescribed for its dual action of improving mood while promoting restful sleep, making it especially useful in cases where depression coexists with sleep disturbances.
TRAZOSIG 100 works by modulating serotonin levels in the brain, primarily blocking serotonin type 2 (5-HT2) receptors and inhibiting serotonin reuptake. This combined mechanism helps restore emotional balance while minimizing overstimulation, offering therapeutic benefit for both mood disorders and sleep problems.
Antidepressant / Anxiolytic / Hypnotic
Trazodone selectively inhibits serotonin reuptake and blocks 5-HT2 receptors, enhancing serotonin activity in the central nervous system. This dual mechanism improves mood and sleep architecture without causing the stimulating effects commonly seen with other antidepressants.
Major Depressive Disorder (MDD)
Anxiety Disorders
Insomnia (particularly depression-related)
Post-Traumatic Stress Disorder (off-label)
Chronic pain syndromes (off-label)
Treats depression and associated sleep disorders
Less sexual dysfunction compared to SSRIs
Lower risk of dependency vs. benzodiazepines
Non-habit forming sedative effect
May help with fibromyalgia-related sleep issues
Adults (Depression): 150 mg/day in divided doses (initial), titrated up to 300–400 mg/day
For insomnia: Often administered as 50–100 mg at bedtime
Should be taken with food to improve absorption
Dose adjustments based on clinical response and tolerability
Use cautiously in patients with cardiac disease or arrhythmia
May cause drowsiness—avoid driving or operating machinery
Risk of serotonin syndrome if combined with serotonergic agents
Avoid alcohol and CNS depressants
Not recommended during pregnancy unless absolutely necessary
Drowsiness or sedation
Dry mouth
Dizziness or orthostatic hypotension
Blurred vision
Nausea
Rare: priapism (prolonged erection), QT prolongation
BLUEPILL EXPRESS is a globally trusted third-party manufacturer and exporter of high-quality generic pharmaceuticals. TRAZOSIG 100 TABLET is produced under stringent WHO-GMP and ISO-certified conditions, ensuring efficacy, safety, and compliance with international regulatory standards.
High-grade active pharmaceutical ingredients (APIs)
Private labeling and custom branding available
Reliable documentation: COA, MSDS, stability data, export paperwork
Export coverage across Africa, Asia, Latin America, CIS, and Europe
Flexible MOQ and logistics support for global partners
