Bisacodyl

Bisacodyl is a stimulant laxative widely used for the short-term relief of constipation, preparation for colonoscopy, and bowel evacuation prior to surgical or diagnostic procedures. Known for its rapid onset of action and predictable bowel movement induction, Bisacodyl is a crucial medication in gastrointestinal care across hospital, retail, and clinical settings.

Bisacodyl acts directly on the colon to stimulate peristalsis and promote bowel motility. It is often preferred for its efficacy, safety profile, and diverse dosage forms, including oral tablets and suppositories.

At BluepillExpress, we offer comprehensive third-party manufacturing services for Bisacodyl in multiple formulations. With a commitment to global regulatory compliance, scalable production, and customizable packaging, we empower healthcare brands, NGOs, and procurement agencies worldwide to deliver quality laxative solutions under their own label.

About BluepillExpress

BluepillExpress is a leading Indian third-party pharmaceutical manufacturer and exporter with global recognition for affordable, quality-assured formulations. Our capabilities span the entire pharmaceutical supply chain, from formulation development and production to export and registration.

We specialize in:

• WHO-GMP certified contract manufacturing
• IP, BP, USP-compliant dosage forms
• Regulatory support (COPP, CTD/ACTD dossiers)
• Custom packaging and private labeling
• Worldwide logistics and distribution

BluepillExpress is trusted by government health programs, non-profits, and private pharmaceutical companies for consistent quality, timely delivery, and complete documentation support.

Pharmacological Classification

• Generic Name: Bisacodyl
• Pharmacological Class: Stimulant Laxative
• Therapeutic Category: Gastrointestinal / Bowel Regulator
• Mechanism of Action: Direct stimulation of intestinal motility
• Available Forms: Oral tablets and rectal suppositories
• Standard Dosages: 5 mg (tablets), 10 mg (suppositories)

Mechanism of Action

Bisacodyl acts locally in the colon by stimulating enteric nerves, thereby increasing the motility of the intestines and facilitating water accumulation in the bowel. This dual action:

• Enhances peristaltic activity, pushing stool through the colon
• Promotes softening of stools, easing defecation
• Induces a predictable bowel movement within 6 to 12 hours (oral) or 15 to 60 minutes (rectal)

This makes Bisacodyl suitable for both therapeutic constipation relief and bowel preparation protocols.

Therapeutic Indications

Bisacodyl is widely used in:

• Occasional constipation
• Bowel cleansing before colonoscopy or surgery
• Evacuation of the bowel in patients with spinal cord injury
• Post-operative bowel stimulation
• Adjunctive treatment for IBS with constipation
• Pre-delivery bowel emptying in obstetrics

Its rapid efficacy and ease of administration make it ideal for both outpatient and inpatient care.

Dosage Forms and Strengths by BluepillExpress

We manufacture Bisacodyl in two primary formulations, suitable for both adult and pediatric use:

1. Bisacodyl Tablets (Enteric-Coated)

• Strengths: 5 mg (standard adult dose)
• Form: Enteric-coated tablets to prevent gastric irritation
• Packaging: Blister strips (10×10), bottles (100s, 500s), or bulk packaging
• Shelf life: 36 months

2. Bisacodyl Suppositories

• Strengths: 10 mg
• Form: Solid rectal insert with easy-melt base
• Packaging: PVC strips, individually wrapped, or unit-dose blisters
• Shelf life: 24 months

We can customize packaging and formulation upon request to meet the requirements of public health programs, tender submissions, or branded private labels.

Manufacturing Infrastructure

BluepillExpress’s production facility adheres to WHO-GMP and ISO 9001:2015 standards and is equipped with state-of-the-art machinery for both solid oral dosage forms and suppositories.

Highlights of Our Facility:

• High-speed tablet compression and enteric coating lines
• Dedicated suppository molding and sealing machines
• Cleanroom environments with controlled temperature and humidity
• In-house formulation R&D and quality testing labs
• Dedicated packaging zones with blister sealing and labeling automation

With a production capacity of millions of tablets and suppositories per month, we are equipped to handle both bulk manufacturing and low-volume specialty orders.

Quality Control and Quality Assurance

Our Quality Management System ensures product safety, identity, strength, and purity throughout the lifecycle of the product.

In-House QC Tests:

• API identity, assay, and purity
• Tablet disintegration and dissolution tests
• Suppository softening point and release rate
• Microbial limit and sterility tests
• Content uniformity and hardness testing
• Accelerated and real-time stability studies
• Enteric coating integrity (for tablets)

Each batch is issued with:

• Certificate of Analysis (COA)
• Batch Manufacturing Records (BMR)
• Raw Material and Finished Product Specs
• Stability and Packaging Validation Reports

We strictly follow guidelines from IP, BP, and USP pharmacopoeias and ensure 100% traceability from raw material to finished product.

Packaging and Labeling Solutions

We offer tailor-made packaging options that comply with international shipping and shelf-life standards. Our packaging lines are flexible, allowing branding for multiple markets.

Packaging Options:

• Tablets:
  • Alu-Alu blister packs
  • PVC/Alu blister strips
  • HDPE bottles with desiccants
• Suppositories:
  • PVC strip with peelable foil
  • PVC/PE unit-dose packs
  • Tamper-proof cartons with inserts

Labeling Services:

• Multilingual labels for Africa, CIS, Asia, Latin America
• Barcode integration, QR codes for tracking
• Custom branding with your logo and color scheme
• Regulatory-compliant PILs and outer cartons

We maintain global export packaging norms to protect product integrity through varied climates and transport conditions.

Regulatory Documentation and Support

BluepillExpress provides comprehensive documentation to assist in product registration across diverse regulatory environments.

Documentation Includes:

• WHO-GMP Certificate
• Certificate of Pharmaceutical Product (COPP)
• Certificate of Analysis (COA)
• Free Sale Certificate
• Certificate of Origin
• CTD/ACTD-compliant dossiers
• Product specs and method of analysis (MOA)
• Mockups and final artwork for packaging

We offer expert guidance for filing with:

• NAFDAC (Nigeria)
• PPB (Kenya)
• FMHACA (Ethiopia)
• SFDA (Saudi Arabia)
• DRAP (Pakistan)
• Other national authorities across Africa, Asia, CIS, and the Middle East

Private Label and Contract Manufacturing Workflow

We make third-party manufacturing simple and efficient through our streamlined collaboration process.

How It Works:

1. Requirement Finalization: Choose dosage form, strength, and market
2. Quotation & Agreement: Get detailed pricing and production schedule
3. Artwork & Packaging: Share your brand specifications or let us design
4. Sample Development: We produce samples for your testing or registration
5. Commercial Production: Full-scale GMP-compliant manufacturing
6. Packaging & Labeling: Your branding applied professionally
7. Shipping & Documentation: Products dispatched with full paperwork

We support MOQs as low as 50,000 units, making us ideal for both small and large-scale distributors and marketers.

Global Reach and Market Presence

BluepillExpress has an active global presence and supplies Bisacodyl to clients in over 50 countries.

Major Export Regions:

• Africa: Nigeria, Kenya, Ghana, Sudan, Uganda, Tanzania
• Asia: Nepal, Bangladesh, Myanmar, Cambodia
• Middle East: Iraq, Yemen, Jordan, UAE
• Latin America & Caribbean: Haiti, Dominican Republic, Peru, Bolivia
• CIS Countries: Kazakhstan, Uzbekistan, Kyrgyzstan

Our clientele includes:

• Ministry of Health suppliers
• NGO procurement channels (UNICEF, WHO-funded programs)
• Private pharma brands and OTC marketers
• Hospitals and institutional healthcare providers

We also provide emergency supply batches and tender participation support.

Sustainability and Ethical Practices

BluepillExpress is committed to sustainable, ethical, and socially responsible pharmaceutical manufacturing:

• Zero-discharge effluent treatment
• Energy-efficient production systems
• Eco-friendly packaging options
• Ethical workforce practices: no child labor, gender-neutral employment
• Community health programs and NGO partnerships

We strive to meet the United Nations Sustainable Development Goals (SDGs) in our operations.

Why Choose BluepillExpress for Bisacodyl Manufacturing?

• WHO-GMP and ISO certified facility
• IP/BP/USP-compliant Bisacodyl formulations
• Flexible MOQs and competitive pricing
• Full private-label and branding support
• CTD/ACTD dossier preparation
• Strong global logistics and customs clearance support
• Ethical, scalable, and compliant production

From formulation to final delivery, BluepillExpress ensures efficacy, reliability, and regulatory compliance.

Conclusion

Bisacodyl remains a critical drug in the management of constipation and bowel preparation procedures across both clinical and retail settings. With growing awareness of digestive health and demand for safe OTC laxatives, Bisacodyl offers significant commercial potential.

BluepillExpress is your trusted partner for the third-party manufacturing of Bisacodyl, offering complete solutions that combine global manufacturing standards, flexible branding, and timely execution. Whether you are a government buyer, hospital supplier, or OTC brand, we help you deliver safe, effective gastrointestinal solutions to your market.