TELMISARTAN

Telmisartan is a potent angiotensin II receptor blocker (ARB) used globally for the management of hypertension and cardiovascular risk reduction. It acts by blocking the binding of angiotensin II to the AT1 receptor, resulting in vasodilation, reduced blood pressure, and improved cardiovascular outcomes.

At Bluepill Express, we are a trusted manufacturer and exporter of high-quality Telmisartan API that complies with IP, BP, USP, and EP pharmacopeial standards. Our advanced production systems ensure superior purity, consistent particle size, and excellent stability, making it ideal for formulation into tablets and fixed-dose combinations (such as Telmisartan with Hydrochlorothiazide or Amlodipine).

Each batch of Telmisartan API undergoes stringent in-house testing and quality validation in accordance with WHO-GMP, ISO 9001:2015, and cGMP regulations, ensuring global acceptance for pharmaceutical manufacturing and export.

Pharmacological Information:

• Therapeutic Category: Antihypertensive
• Pharmacological Class: Angiotensin II Receptor Blocker (ARB)
• CAS Number: 144701-48-4
• Molecular Formula: C33H30N4O2
• Molecular Weight: 514.63 g/mol
• Appearance: White to off-white crystalline powder
• Solubility: Practically insoluble in water; soluble in strong acids and organic solvents
• Melting Point: 261°C – 263°C
• Storage: Store in a cool, dry place below 25°C, protected from light and moisture

Mode of Action:

Telmisartan selectively blocks the angiotensin II type 1 (AT1) receptor, preventing vasoconstriction and the release of aldosterone. This reduces sodium retention, decreases vascular resistance, and lowers blood pressure, while maintaining renal and cardiac protection.

Applications and Uses:

• Hypertension Management – Controls blood pressure effectively
• Cardiovascular Protection – Reduces risk of heart attack and stroke
• Chronic Heart Failure Support – Helps improve cardiac performance
• Combination Therapy – Commonly formulated with Amlodipine, Hydrochlorothiazide, or Metoprolol
• Pharmaceutical Formulations – Tablets (20 mg, 40 mg, 80 mg)

Technical Specifications:

• Assay (Purity): ≥ 99.0%
• Identification: IR spectrum conforms to reference standard
• Loss on Drying: ≤ 0.5%
• Residue on Ignition: ≤ 0.1%
• Heavy Metals: ≤ 10 ppm
• Related Substances: ≤ 0.2% (individual impurity)
• Particle Size Distribution: Optimized for uniform tablet formulation
• Microbial Limits: Complies with pharmacopeial standards

Manufacturing & Quality Assurance – Bluepill Express:

• Manufactured under WHO-GMP, ISO, and cGMP certified units
• High-purity crystalline Telmisartan API suitable for direct compression formulations
• Validated analytical methods (HPLC, GC, IR) for every production batch
• Documentation support: COA, MSDS, TDS, and stability reports provided
• Regulatory compliance: IP / BP / USP / EP

Packaging & Export Details:

• Available Packs: 1 kg, 5 kg, 10 kg, 25 kg HDPE drums with double poly liners
• Shelf Life: 36 months from manufacturing date
• Labeling: Export-compliant with batch number, manufacturing, and expiry details
• Export Regions: Asia, Africa, Europe, Latin America, and the Middle East
• Documents Provided:
  • Certificate of Analysis (COA)
  • Material Safety Data Sheet (MSDS)
  • Technical Data Sheet (TDS)
  • Stability Data (on request)
  • Non-GMO, BSE/TSE-free, and Allergen-free declarations