QUININE SULPHATE

Quinine Sulphate is a naturally derived antimalarial alkaloid, primarily used for the treatment of malaria caused by Plasmodium falciparum and other Plasmodium species. Extracted from the bark of the Cinchona tree, it has been used for centuries as a potent antipyretic, analgesic, and antimalarial agent.

At Bluepill Express, we manufacture and export high-purity Quinine Sulphate API that complies with IP, BP, USP, and EP standards. Our product is produced under WHO-GMP, ISO 9001:2015, and cGMP-certified facilities, ensuring exceptional quality, purity, and stability for global pharmaceutical formulations.

This API serves as a critical component in antimalarial tablets, capsules, and injectables, and is also used as an ingredient in muscle relaxant and anti-cramp formulations due to its ability to reduce muscle excitability.

Therapeutic Applications:

• Treatment of Malaria (especially chloroquine-resistant strains of Plasmodium falciparum)
• Relief of nocturnal leg cramps
• Antipyretic and analgesic applications in certain formulations
• Used in tonic water production in microdoses as a flavoring compound

Mechanism of Action:

Quinine Sulphate acts by interfering with the parasite’s ability to digest hemoglobin, leading to toxic accumulation within the malaria parasite and subsequent death of the organism. It targets the erythrocytic stages of Plasmodium, thereby relieving symptoms of malaria such as fever, chills, and fatigue.

Technical Specifications:

• Chemical Name: Quinine Sulphate dihydrate
• Molecular Formula: C₂₀H₂₄N₂O₂·H₂SO₄·2H₂O
• Molecular Weight: 782.96 g/mol
• CAS Number: 6119-47-7
• Appearance: White or off-white crystalline powder
• Assay: NLT 98.0% and NMT 101.0% (on anhydrous basis)
• Solubility: Freely soluble in water; slightly soluble in alcohol
• Melting Point: 205°C – 210°C
• Storage Conditions: Store below 25°C, protected from light and moisture

Pharmacological Classification:

• Therapeutic Class: Antimalarial / Antipyretic / Analgesic
• Pharmacopoeial Standards: IP / BP / USP / EP
• Dosage Form Applications: Tablets, Capsules, Injections

Manufacturing Excellence at Bluepill Express:

• Produced under WHO-GMP, ISO, and cGMP certified facilities
• High assay value (≥99%) ensuring superior efficacy
• HPLC-tested for purity and impurity profiling
• Batch reproducibility and excellent solubility profile
• DMF-ready with all regulatory and quality documents available

Advantages of Bluepill Express Quinine Sulphate API:

• Pharmacopeial-grade compliant with global standards
• DMF & COA support for international registration
• Customizable bulk packaging for easy export logistics
• Tested for heavy metals, microbial limits, and moisture content
• Long shelf life under controlled conditions

Packaging & Export Information:

• Standard Packing: 1 kg, 5 kg, or 25 kg HDPE drums with double LDPE liners
• Labeling: As per export and pharmacopeial norms
• Shelf Life: 3 years under standard storage conditions
• Export Markets: Africa, Asia, Middle East, Latin America, Europe
• Documentation Provided:
  • Certificate of Analysis (COA)
  • Material Safety Data Sheet (MSDS)
  • Stability data
  • Technical Data Sheet (TDS)