PARACETAMOL CRYSTALS

Paracetamol Crystals (also known as acetaminophen) are a widely used analgesic and antipyretic agent effective for the treatment of pain, fever, and mild inflammatory conditions. It acts by inhibiting prostaglandin synthesis in the CNS and exhibits minimal anti-inflammatory activity peripherally, making it safe for use across all age groups when administered at therapeutic doses.

At Bluepill Express, we manufacture and export pharmaceutical-grade Paracetamol Crystals API that meets IP, BP, USP, and EP pharmacopeial standards. Produced under WHO-GMP, ISO, and cGMP-certified facilities, our API ensures high purity, crystalline consistency, and excellent stability, suitable for tablets, capsules, suspensions, and granules.

Each batch undergoes stringent quality testing, including HPLC, IR spectroscopy, and microbial limits, ensuring reliable and consistent performance for global pharmaceutical manufacturers.

Pharmacological Information:

• Therapeutic Class: Analgesic / Antipyretic
• Pharmacological Category: COX inhibitor (central)
• CAS Number: 103-90-2
• Molecular Formula: C8H9NO2
• Molecular Weight: 151.16 g/mol
• Appearance: White crystalline powder
• Solubility: Slightly soluble in water, freely soluble in hot water, ethanol, and methanol
• Melting Point: 168°C – 172°C
• Storage: Store in a cool, dry place below 25°C, protected from light and moisture

Mode of Action:

Paracetamol primarily inhibits cyclooxygenase (COX) enzymes in the CNS, reducing prostaglandin synthesis and lowering fever and alleviating pain. Its minimal peripheral COX inhibition results in low gastrointestinal irritation, making it safer than conventional NSAIDs.

Applications and Uses:

• Fever Reduction (Antipyretic) – Effective in adults and children
• Pain Relief (Analgesic) – For headaches, toothaches, muscle pain, and arthritis
• Combination Therapy – Often combined with NSAIDs, opioids, or cold & flu formulations
• Pharmaceutical Formulations – Tablets, capsules, suspensions, granules, and effervescent powders

Technical Specifications:

• Assay (Purity): ≥ 99.5%
• Identification: IR spectrum matches reference standard
• Loss on Drying: ≤ 0.5%
• Residue on Ignition: ≤ 0.1%
• Heavy Metals: ≤ 10 ppm
• Particle Size: Crystalline, optimized for uniform formulation
• Related Substances: ≤ 0.2% (individual impurity)
• Microbial Limits: Complies with pharmacopeial specifications

Manufacturing & Quality Assurance – Bluepill Express:

• Produced under WHO-GMP, ISO 9001:2015, and cGMP-certified facilities
• High-purity crystalline API suitable for all oral formulations
• COA, MSDS, and TDS provided with each batch
• HPLC-tested for purity, impurity profiling, and stability
• Pharmacopeial compliance: IP / BP / USP / EP

Packaging & Export Details:

• Available Packs: 1 kg, 5 kg, 10 kg, 25 kg HDPE drums with inner liner
• Shelf Life: 36 months from manufacturing date
• Labeling: Export-compliant with batch number and origin
• Export Markets: Africa, Asia, Europe, Middle East, Latin America
• Documentation Provided:
  • Certificate of Analysis (COA)
  • Material Safety Data Sheet (MSDS)
  • Technical Data Sheet (TDS)
  • Stability Data (on request)
  • Non-GMO & Allergen-Free Declarations