IndiaMart
FIEO
Memantine Hydrochloride is a centrally acting NMDA (N-Methyl-D-Aspartate) receptor antagonist primarily used for the management of moderate to severe Alzheimer’s disease. By modulating glutamatergic neurotransmission, it helps reduce excitotoxicity and neuronal damage, thereby improving cognitive function, memory, and daily functioning in patients with neurodegenerative disorders.
At Bluepill Express, we manufacture and export pharmaceutical-grade Memantine Hydrochloride API that meets IP, BP, USP, and EP pharmacopeial standards. Produced under WHO-GMP, ISO, and cGMP-certified facilities, our API ensures high purity, crystalline consistency, and excellent stability, suitable for tablets, capsules, and oral solutions.
Each batch undergoes rigorous quality testing, including HPLC, IR spectroscopy, and microbial analysis, ensuring reliable performance for global pharmaceutical manufacturers.
Pharmacological Information:
- Therapeutic Class: Anti-Alzheimer / NMDA Receptor Antagonist
- Pharmacological Category: Neuroprotective Agent
- CAS Number: 19982-08-2
- Molecular Formula: C12H21N·HCl
- Molecular Weight: 215.76 g/mol
- Appearance: White to off-white crystalline powder
- Solubility: Soluble in water, slightly soluble in ethanol
- Melting Point: 255°C – 257°C
- Storage: Store in a cool, dry place below 25°C, protected from light
Mode of Action:
Memantine Hydrochloride blocks overactive NMDA receptors in the brain, preventing excessive calcium influx that can cause neuronal damage. This mechanism helps maintain cognitive function and slows the progression of Alzheimer’s symptoms.
Applications and Uses:
- Moderate to Severe Alzheimer’s Disease – Improves cognition and daily living
- Neurodegenerative Disorders – Off-label use in Parkinson’s disease dementia and other cognitive impairments
- Combination Therapy – Often combined with cholinesterase inhibitors
- Pharmaceutical Formulations – Tablets, capsules, and oral solutions
Technical Specifications:
- Assay (Purity): ≥ 99.0%
- Identification: IR spectrum matches reference standard
- Loss on Drying: ≤ 0.5%
- Residue on Ignition: ≤ 0.1%
- Heavy Metals: ≤ 10 ppm
- Particle Size: Optimized for uniform formulation
- Related Substances: ≤ 0.2% (individual impurity)
- Microbial Limits: Complies with pharmacopeial standards
Manufacturing & Quality Assurance – Bluepill Express:
- Produced under WHO-GMP, ISO 9001:2015, and cGMP-certified facilities
- High-purity crystalline API suitable for various oral dosage forms
- COA, MSDS, and TDS provided for each batch
- HPLC-tested for purity, impurity profiling, and stability
- Pharmacopeial compliance: IP / BP / USP / EP
Packaging & Export Details:
- Available Packs: 1 kg, 5 kg, 10 kg, 25 kg HDPE drums with inner liner
- Shelf Life: 36 months from manufacturing date
- Labeling: Export-compliant with batch number and origin
- Export Markets: Africa, Asia, Europe, Middle East, Latin America
- Documentation Provided:
- Certificate of Analysis (COA)
- Material Safety Data Sheet (MSDS)
- Technical Data Sheet (TDS)
- Stability Data (on request)
- Non-GMO & Allergen-Free Declarations
