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Escitalopram Oxalate is a highly effective Selective Serotonin Reuptake Inhibitor (SSRI) used in the treatment of depression, anxiety disorders, panic disorder, and obsessive-compulsive disorder (OCD). It works by enhancing serotonin activity in the brain, helping restore emotional balance and mental well-being.
At Bluepill Express, we manufacture and export Escitalopram Oxalate API with high purity (≥99%), consistent crystalline form, and excellent stability. Produced in WHO-GMP, ISO 9001:2015, and cGMP-certified facilities, our API meets all international pharmacopeial standards (IP/BP/USP/EP).
Escitalopram Oxalate is the S-enantiomer of Citalopram, providing superior therapeutic efficacy with fewer side effects. It’s widely used in oral solid dosage formulations such as tablets and capsules and offers excellent bioavailability for global antidepressant products.
Therapeutic Applications:
- Major depressive disorder (MDD)
- Generalized anxiety disorder (GAD)
- Panic disorder and social anxiety disorder
- Obsessive-compulsive disorder (OCD)
- Post-traumatic stress disorder (PTSD)
Mechanism of Action:
Escitalopram Oxalate selectively inhibits the reuptake of serotonin (5-HT) at the presynaptic membrane, increasing serotonin concentration in the synaptic cleft. This leads to improved mood, reduced anxiety, and enhanced emotional stability without significant sedative or cardiovascular effects.
Technical Specifications:
- Chemical Name: (S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile oxalate
- Molecular Formula: C₂₀H₂₁FN₂O₃·C₂H₂O₄
- Molecular Weight: 414.40 g/mol
- CAS Number: 219861-08-2
- Appearance: White to off-white crystalline powder
- Assay (on dried basis): NLT 99.0% and NMT 101.0%
- Solubility: Slightly soluble in water; soluble in methanol and ethanol
- Storage Conditions: Store below 25°C, protected from light and moisture
Pharmacological Classification:
- Therapeutic Class: Antidepressant / SSRI
- Pharmacopoeial Standards: IP / BP / USP / EP
- Dosage Form Applications:
- Oral tablets (5 mg, 10 mg, 20 mg)
- Capsules and oral drops
- Extended-release formulations
Manufacturing & Quality Standards – Bluepill Express:
- Manufactured under WHO-GMP, ISO 9001:2015, and cGMP compliance
- High-purity API verified using HPLC, NMR, and FTIR
- Low residual solvent content per ICH Q3C guidelines
- Excellent stability and controlled particle size distribution
- Complete COA, MSDS, and DMF documentation available
- Batch-to-batch consistency with validated analytical methods
Advantages of Bluepill Express Escitalopram Oxalate API:
- High assay (≥99%) with superior enantiomeric purity
- Low impurity and moisture levels
- DMF-ready documentation for global registration
- WHO-GMP-certified manufacturing unit
- Proven stability under long-term and accelerated conditions
Packaging & Export Details:
- Packaging Sizes: 1 kg / 5 kg / 25 kg HDPE drums with double LDPE liners
- Shelf Life: 3 years when stored under recommended conditions
- Labeling: Complies with pharmacopeial and export standards
- Export Markets: Europe, Latin America, Middle East, Africa, and Southeast Asia
- Documentation Provided:
- Certificate of Analysis (COA)
- Material Safety Data Sheet (MSDS)
- Drug Master File (DMF – on request)
- Stability and validation reports
