CARBOCISTEINE

Carbocisteine API (also known as S-Carboxymethyl-L-Cysteine) is a powerful mucolytic agent used in the treatment of respiratory disorders associated with excessive mucus production, such as chronic obstructive pulmonary disease (COPD), bronchitis, asthma, and sinusitis.

At Bluepill Express, we are a WHO-GMP, ISO 9001:2015, and cGMP-certified manufacturer and exporter of Carbocisteine Active Pharmaceutical Ingredient (API). Our Carbocisteine is produced with high purity, consistent quality, and compliance to IP/BP/USP standards, ensuring optimal efficacy and stability for formulation use.

Carbocisteine works by breaking down and thinning mucus, making it less viscous and easier to expel from the respiratory tract. This action helps clear airways, reduce coughing, and improve breathing efficiency. It is widely used in both prescription and over-the-counter formulations such as syrups, capsules, and tablets.

Therapeutic Applications:

• Chronic bronchitis
• Chronic obstructive pulmonary disease (COPD)
• Asthma with mucus hypersecretion
• Sinusitis and rhinitis
• Respiratory tract infections with thick sputum

Mechanism of Action:

Carbocisteine acts by regulating the viscosity of mucus. It modifies the structure of mucopolysaccharides in sputum, reducing its thickness and adhesiveness. This enhances mucociliary clearance and promotes easier elimination of mucus, improving respiratory comfort and function.

Technical Specifications:

• Chemical Name: (R)-2-Amino-3-(carboxymethylsulfanyl)propanoic acid
• Molecular Formula: C₅H₉NO₄S
• Molecular Weight: 179.19 g/mol
• CAS Number: 22711-93-1
• Description: White to off-white crystalline powder
• Assay (on dried basis): NLT 98.0% and NMT 101.0%
• Melting Point: 204°C – 208°C
• Solubility: Freely soluble in water, slightly soluble in ethanol
• Storage Conditions: Store in a tightly closed container below 30°C, protected from moisture and light

Pharmacological Classification:

• Therapeutic Class: Expectorant / Mucolytic
• Pharmacopoeial Standards: IP / BP / USP / EP
• Dosage Form Applications:
  • Oral syrup (250 mg/5 mL, 500 mg/5 mL)
  • Capsules and tablets (375 mg, 750 mg)
  • Combination formulations with bronchodilators and antihistamines

Quality & Manufacturing – Bluepill Express Standards:

• Manufactured in WHO-GMP, ISO, and cGMP-certified facilities
• High assay purity (≥99%), minimal impurities
• Verified through HPLC and IR spectroscopic methods
• Pharmacopeial grade compliance (USP/BP/IP)
• DMF, COA, and MSDS available upon request
• Manufactured using controlled temperature and humidity systems for stability

Advantages of Bluepill Express Carbocisteine API:

• Superior solubility and flow properties for formulation convenience
• Batch-to-batch uniformity with strict quality controls
• Compliant with global pharmacopeias (USP, BP, IP)
• Regulatory-ready documentation for easy product registration
• Flexible packaging options for bulk exports

Packaging & Export Details:

• Packaging Sizes: 1 kg / 5 kg / 25 kg HDPE drums with inner liner
• Shelf Life: 36 months (under recommended storage)
• Labeling: In accordance with global regulatory norms
• Export Markets: Europe, Asia-Pacific, Africa, Middle East, Latin America
• Documentation Provided:
  • Certificate of Analysis (COA)
  • Material Safety Data Sheet (MSDS)
  • Drug Master File (DMF – on request)
  • Stability data and TSE/BSE-free certificates