Mefloquine Hydrochloride

Mefloquine Hydrochloride is a well-established antimalarial drug used both for prophylaxis and treatment of malaria, particularly infections caused by Plasmodium falciparum, including chloroquine-resistant strains. It remains a vital pharmaceutical in the global fight against malaria, especially in tropical and sub-tropical regions where transmission is endemic.

At BluepillExpress, we specialize in the third-party manufacturing of Mefloquine Hydrochloride with a commitment to global compliance, high-quality formulation, and timely delivery. Our robust manufacturing facilities are WHO-GMP and ISO 9001:2015 certified, ensuring every product batch meets international standards for quality, efficacy, and safety.

What Is Mefloquine Hydrochloride?

Mefloquine Hydrochloride is a synthetic antimalarial belonging to the quinoline methanol class. It is structurally related to quinine and is particularly effective in areas with multi-drug resistant malaria strains. Mefloquine acts by interfering with the parasite’s ability to degrade hemoglobin, ultimately leading to its death.

Key Therapeutic Applications:

• Prophylaxis of malaria for travelers and populations in endemic areas
• Treatment of mild to moderate acute malaria, especially when resistant to other therapies
• Used in combination therapies with artemisinin derivatives (in some countries)
• Off-label uses in certain parasitic infections and as a second-line agent

Its long half-life allows for once-weekly dosing for prophylaxis and single-dose treatment regimens, making it a convenient and patient-friendly antimalarial solution.

Why Choose BluepillExpress for Mefloquine Hydrochloride Manufacturing?

BluepillExpress offers fully integrated, end-to-end contract manufacturing solutions for Mefloquine Hydrochloride. With years of pharmaceutical manufacturing experience, we empower our clients with:

• Global quality standards (WHO-GMP, ISO)
• Regulatory support for international registrations
• Low and high MOQ options for emerging and established brands
• Custom branding, labeling, and private/white label services
• Complete technical dossiers for CTD/ACTD submissions
• Timely production, packaging, and export logistics
• Ethical sourcing and validated raw material suppliers

Whether you’re a government buyer, pharmaceutical company, or humanitarian organization, our scalable capacity and global export expertise make us the ideal partner for manufacturing Mefloquine Hydrochloride.

Mefloquine Hydrochloride Formulations Offered

We manufacture Mefloquine Hydrochloride in tablet form, the most widely accepted and WHO-recommended route of administration.

1. Mefloquine Hydrochloride Tablets 250 mg

• Dosage Form: Oral tablet
• Composition: Equivalent to 228 mg base
• Packaging: Alu-Alu or blister strip packs (10×1, 10×10, or as required)
• Indication: Prophylaxis and treatment of malaria
• Shelf Life: 24–36 months
• Storage: Store in a cool, dry place, away from direct sunlight

2. Customized Strengths and Fixed-Dose Combinations (on request)

• Mefloquine + Artesunate (FDC for acute malaria)
• Pediatric-friendly formulations (dispersible tablets)
• Mefloquine API supply (bulk quantities for licensed manufacturers)

All our formulations comply with USP, BP, IP, and EP pharmacopeial standards, and are available for public tenders, NGOs, and institutional buyers.

Manufacturing Facility Capabilities

Our state-of-the-art oral solid dosage manufacturing facility includes the following:

• Automatic granulation and tablet compression lines
• Isolated areas for API handling and blending
• In-process quality testing stations
• High-speed blister and alu-alu packaging lines
• Dust extraction systems to manage potent compound exposure
• HVAC-controlled cleanroom environments (ISO Class 8)
• Validated systems for cleaning, cross-contamination control, and material traceability

Our commitment to cGMP ensures consistency, safety, and product traceability at every production stage.

Quality Assurance and Quality Control (QA/QC)

Our in-house QA/QC departments are central to our production philosophy, ensuring every batch of Mefloquine Hydrochloride meets global quality benchmarks.

Quality Control Includes:

• Identity and assay of Mefloquine Hydrochloride
• Dissolution profile and disintegration testing
• Uniformity of weight and content
• Microbial load and endotoxin testing
• Stability studies (real-time and accelerated) under ICH guidelines
• Moisture content, pH, and physical inspection tests

We supply comprehensive documentation with every batch:

• Certificate of Analysis (COA)
• Batch Manufacturing Record (BMR)
• Method of Analysis (MOA)
• Material Safety Data Sheet (MSDS)
• Stability study reports
• Packaging and labeling compliance certificates

Regulatory Support and Dossier Preparation

BluepillExpress provides full regulatory assistance for clients wishing to register Mefloquine Hydrochloride in regulated, semi-regulated, and unregulated markets.

We Offer:

• CTD/eCTD Dossiers
• WHO-GMP Certificate
• Certificate of Pharmaceutical Product (CoPP)
• Free Sale Certificate (FSC)
• Site Master File (SMF)
• Stability Data and Product Development Report
• Bioequivalence and Toxicology Study Support (upon request)
• Technical data sheets and declarations of conformity

We’ve successfully assisted partners in registering Mefloquine Hydrochloride across Africa, Southeast Asia, Latin America, and the CIS region.

Packaging & Labeling Customization

Proper packaging is essential for both medicinal integrity and regulatory compliance. BluepillExpress provides internationally compatible, patient-safe, and durable packaging formats.

Packaging Options:

• Alu-alu blister packs
• PVC/Aluminum strip packs
• Secondary boxes with multi-language inserts
• Customized artwork and branding
• WHO-compliant labeling for public health programs
• Barcoding and serialization (GS1 standard)
• Tamper-evident and moisture-resistant cartons

We offer private and white label manufacturing services, assisting clients in brand development, packaging design, and compliance with local labeling laws.

Private Label & White Label Services

For businesses looking to launch their own antimalarial product range, our private label and white label solutions offer a fast, compliant, and high-quality route to market.

Services Include:

• Custom brand/logo/label design
• Regulatory documentation under your brand
• Trademark guidance and packaging approvals
• Product photography and marketing support
• NDA agreements for brand protection
• Market-specific label customization
• Low MOQs for trial batches and new launches

Our experienced marketing and design teams collaborate with clients to build a unique brand identity while ensuring full regulatory and therapeutic compliance.

Export & Global Logistics Services

BluepillExpress is a trusted exporter of antimalarial drugs, including Mefloquine Hydrochloride, to over 30 countries across:

• Africa (Nigeria, Ghana, Uganda, Tanzania)
• Middle East (Yemen, Iraq, Jordan)
• Southeast Asia (Myanmar, Cambodia, Vietnam)
• CIS Countries (Uzbekistan, Kyrgyzstan)
• Latin America (Peru, Bolivia, Nicaragua)

Export Support Includes:

• Sea, air, and multimodal logistics
• EXW, FOB, CIF, and DDP shipping terms
• Cold chain solutions (if required)
• Complete export documentation
• Regulatory pre-shipment testing
• Custom clearance and freight forwarding
• Global tracking and dispatch notifications

We are capable of handling bulk orders, tender supplies, emergency shipments, and custom delivery schedules with full visibility.

Minimum Order Quantity (MOQ)

To cater to both large and small buyers, we offer flexible MOQs, including:

• Trial batches for product registration or sampling
• Medium orders for hospital chains and government supplies
• Bulk consignments for international NGOs and health missions
• Annual production contracts for consistent supply needs

MOQ depends on packaging type, formulation, and regulatory requirements. Please contact our commercial team for a tailored quotation.

Client Testimonials

“BluepillExpress provided us with regulatory-ready Mefloquine dossiers and high-quality tablets that were approved without major queries. Professional, responsive, and reliable.”
— Regulatory Affairs Manager, East Africa

“We’ve supplied Mefloquine manufactured by BluepillExpress to over 400 health facilities. The product quality and batch consistency have been excellent.”
— Public Health Procurement Officer, Southeast Asia

“As a startup brand, we were able to launch our private label antimalarial line in under 3 months, thanks to BluepillExpress’s private label program.”
— Pharmaceutical Entrepreneur, Latin America

Conclusion

Mefloquine Hydrochloride continues to play a crucial role in combating malaria, especially in regions facing chloroquine resistance. As global health organizations, national governments, and pharmaceutical brands ramp up their efforts to tackle malaria, partnering with a compliant, capable, and responsive third-party manufacturer becomes essential.

BluepillExpress is proud to support this mission by offering top-tier Mefloquine Hydrochloride manufacturing services—customized to your brand, tailored to your regulatory landscape, and delivered to your global market.

Choose BluepillExpress—your reliable partner in third-party pharmaceutical manufacturing, where quality meets trust and science delivers results.