Metronidazole

Metronidazole is a widely prescribed antiprotozoal and antibacterial agent effective against anaerobic bacteria and certain parasites. Its broad-spectrum antimicrobial activity and excellent tissue penetration make it a primary treatment choice for gastrointestinal infections, gynecological infections, dental infections, surgical prophylaxis, and amoebiasis.

Globally recognized for its therapeutic versatility, Metronidazole remains an essential medicine listed by the World Health Organization (WHO). It is included in both hospital formularies and public health programs across continents.

At BluepillExpress, we offer WHO-GMP-certified third-party manufacturing of high-quality Metronidazole in various dosage forms. Our production capabilities, regulatory expertise, and quality assurance standards enable us to deliver customizable, compliant, and export-ready solutions tailored to your branding and distribution needs.

About BluepillExpress

BluepillExpress is a trusted Indian third-party pharmaceutical manufacturing company specializing in a wide range of anti-infective, gastrointestinal, and general medicine formulations. With certified facilities and a robust supply chain, we support pharmaceutical distributors, institutional buyers, public health authorities, and non-profit organizations worldwide.

Our services include:

• WHO-GMP certified manufacturing
• Private labeling and custom branding
• Regulatory dossier preparation and registration support
• Global logistics, export documentation, and shipping
• Flexible MOQs for emerging markets and startups

With an emphasis on innovation, compliance, and affordability, BluepillExpress ensures that essential medicines like Metronidazole are produced and supplied with utmost care and global standards.

Pharmacological Overview

• Generic Name: Metronidazole
• Pharmacological Class: Nitroimidazole derivative
• Therapeutic Category: Antiprotozoal and Antibacterial agent
• Mechanism of Action: Disruption of DNA synthesis in anaerobic organisms
• Formulations Offered: Tablets, Suspensions, Injections
• Routes of Administration: Oral, Intravenous

Mechanism of Action

Metronidazole enters the cells of anaerobic bacteria and protozoa, where it is reduced by cellular enzymes to reactive nitro radicals. These radicals bind to DNA and inhibit nucleic acid synthesis, ultimately leading to cell death.

This mechanism provides high efficacy against:

• Obligate anaerobes (e.g., Bacteroides, Clostridium)
• Protozoa (e.g., Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis)

Due to its ability to cross the blood-brain barrier and penetrate abscesses, Metronidazole is highly effective in treating deep-seated infections.

Therapeutic Indications

Metronidazole is indicated for the treatment and prophylaxis of a wide range of infections, including:

• Amoebiasis (intestinal and hepatic)
• Giardiasis
• Trichomoniasis
• Bacterial vaginosis
• Pelvic inflammatory disease (PID)
• Anaerobic bacterial infections of the abdomen, pelvis, brain, and lungs
• Dental infections and gingivitis
• H. pylori eradication (as part of combination therapy)
• Post-operative prophylaxis in colorectal surgery
• Sepsis caused by anaerobic organisms

Its affordability, efficacy, and safety make Metronidazole indispensable in both clinical and public health settings.

Dosage Forms and Strengths Manufactured by BluepillExpress

BluepillExpress manufactures Metronidazole in the following standard and customizable dosage forms:

1. Metronidazole Tablets

• Strengths: 200 mg, 400 mg, 500 mg
• Form: Uncoated or film-coated oral tablets
• Packing: Blister strips (10×10), HDPE bottles, or bulk containers
• Shelf Life: 36 months
• Standards: IP, BP, USP available

2. Metronidazole Oral Suspension

• Strength: 200 mg/5 ml
• Form: Ready-to-use flavored liquid
• Packing: 60 ml / 100 ml / 200 ml bottles
• Features: Pediatric-friendly, sugar-free versions on request

3. Metronidazole IV Infusion (on request)

• Strength: 500 mg/100 ml
• Form: Aqueous solution in plastic bottles or infusion bags
• Use: For inpatient hospital supply or emergency use

We offer customized formulations and packaging depending on your country’s regulatory requirements and marketing preferences.

Manufacturing Facilities and Capabilities

Our production units are WHO-GMP, ISO 9001:2015, and Schedule M-compliant, designed to produce Metronidazole formulations with precision and scale.

Manufacturing Highlights:

• Automated tablet compression and syrup filling lines
• Enteric and film-coating units
• Liquid filling with inline quality checks
• Sterile areas for parenteral formulations
• Controlled temperature and humidity zones
• High-volume batch capacity for institutional and government tenders

Our facility produces Metronidazole for export to over 50 countries across Africa, Asia, the Middle East, and Latin America.

Quality Control and Assurance

Every stage of Metronidazole manufacturing at BluepillExpress adheres to a rigorous Quality Management System (QMS). We ensure compliance with IP, BP, and USP pharmacopoeial standards.

In-House QC Includes:

• API purity and identification via HPLC and UV spectroscopy
• Tablet uniformity, disintegration, and dissolution testing
• Microbial limit tests for oral suspension
• pH, viscosity, and stability testing of syrups
• Sterility and endotoxin tests for injectables
• Accelerated and real-time stability testing

Each product batch is issued with:

• Certificate of Analysis (COA)
• Batch Manufacturing Records (BMR)
• Stability Data Sheets
• MSDS and Specifications

BluepillExpress guarantees traceability, consistency, and reliability in every order.

Packaging and Labeling Solutions

We offer custom packaging and private-labeling tailored to your branding and regulatory needs. All packaging is designed to meet international standards for durability, shelf life, and climate control.

Available Packaging:

• Tablets: Blisters (PVC-Alu, Alu-Alu), strip packs, bottles
• Suspensions: Amber or white HDPE bottles with child-resistant caps
• Injectables: Infusion bags, glass or plastic vials (for hospital use)
• Cartons with multilingual printing and barcoding
• Leaflets or inserts as per local authority guidelines

Our team ensures artwork, design, and labeling are compliant with global health regulations and brand presentation requirements.

Regulatory Documentation and Export Support

BluepillExpress provides full regulatory support and documentation to help you register Metronidazole in your target country.

Documentation Provided:

• WHO-GMP Certificate
• Certificate of Pharmaceutical Product (COPP)
• Certificate of Analysis (COA)
• Free Sale Certificate
• Certificate of Origin
• Stability studies (real-time and accelerated)
• Dossier in CTD/ACTD format (on request)
• Product Specification Sheet and MSDS
• Mockups for label and packaging approval

We have supported filings with:

• NAFDAC (Nigeria)
• PPB (Kenya)
• FMHACA (Ethiopia)
• SFDA (Saudi Arabia)
• DRAP (Pakistan)
• MOH registrations across CIS and Asia-Pacific regions

Private Label and Contract Manufacturing Workflow

We simplify the third-party manufacturing process with a transparent, efficient, and supportive model.

Our Process:

1. Product Inquiry: Confirm dosage, formulation, packaging, and target market
2. Quotation & Agreement: Finalize cost, MOQ, and timelines
3. Sample Development: Lab batch for testing or registration
4. Artwork Finalization: Custom branding, multilingual packaging
5. Manufacturing: Commercial production under strict QA protocols
6. Packaging & Dispatch: Global shipping with full documentation
7. After-Sales Support: Regulatory help, reorders, and variations

We accommodate low minimum order quantities and offer special pricing for government or NGO procurement.

Target Markets and Export Reach

BluepillExpress exports Metronidazole to a wide network of countries across:

• Africa: Nigeria, Kenya, Ghana, Sudan, Ethiopia, Zambia
• Asia: Myanmar, Cambodia, Nepal, Bangladesh
• Middle East: Iraq, Jordan, UAE, Yemen
• CIS Countries: Kazakhstan, Armenia, Uzbekistan
• Latin America & Caribbean: Haiti, Dominican Republic, Bolivia

We work with:

• Public health programs
• NGO supply chains (e.g., MSF, UNICEF-funded initiatives)
• Retail and hospital pharmacy chains
• Institutional distributors and tender participants

Sustainability and Ethical Manufacturing

As a responsible pharmaceutical manufacturer, BluepillExpress is committed to ethical practices and sustainable operations:

• Zero-liquid discharge effluent systems
• Energy-efficient equipment and LED lighting
• Recyclable and biodegradable packaging options
• No use of child labor or unethical sourcing
• Inclusive hiring and workplace safety compliance

We align our operations with the United Nations Sustainable Development Goals (SDGs) to improve access to essential medicines and promote responsible manufacturing.

Why Choose BluepillExpress for Metronidazole Manufacturing?

• WHO-GMP certified, export-focused manufacturing
• IP/BP/USP-compliant formulations
• Broad range of dosage forms with flexible customization
• Full private-label and regulatory support
• Competitive pricing for emerging and established markets
• Global logistics and shipping assistance
• Ethical and sustainable operations

From pilot batches to full-scale production, BluepillExpress ensures precision, performance, and partnership in every order.

Conclusion

Metronidazole remains a cornerstone therapy in global health, treating life-threatening and common infections caused by anaerobic bacteria and protozoa. With its essential medicine status, affordability, and multi-form utility, Metronidazole is in high demand across global healthcare systems.

With years of experience in anti-infective pharmaceutical manufacturing, BluepillExpress offers reliable, compliant, and affordable third-party manufacturing of Metronidazole under your brand name. Whether you’re a government agency, humanitarian distributor, or private label marketer, we provide you with everything you need to succeed in your market.