Ciprofloxacin

In an era of rising bacterial infections and the increasing demand for fast-acting, broad-spectrum antimicrobials, Ciprofloxacin remains one of the most widely prescribed fluoroquinolone antibiotics worldwide. Its powerful bactericidal activity, excellent bioavailability, and diverse clinical applications make it a cornerstone in modern antimicrobial therapy.

BluepillExpress, a globally recognized pharmaceutical third-party manufacturer and exporter, is proud to offer high-quality Ciprofloxacin formulations for brands, distributors, healthcare providers, and institutional buyers across regulated and semi-regulated markets. With WHO-GMP-certified manufacturing units and a strong presence in over 40 countries, we bring international compliance, scalability, and consistent product quality to your antibiotic portfolio.

Product Overview

Generic Name: Ciprofloxacin
Pharmacological Class: Fluoroquinolone Antibiotic
Formulations Available:
Ciprofloxacin Tablets
Ciprofloxacin Oral Suspension / Syrup
Ciprofloxacin Eye/Ear Drops
Ciprofloxacin Infusion (IV)
Ciprofloxacin Dispersible Tablets (Pediatric use)

Strengths Offered:
Tablets: 250 mg, 500 mg, 750 mg, 1000 mg
Oral Suspension: 250 mg/5 ml, 500 mg/5 ml
Infusion: 200 mg/100 ml and 400 mg/200 ml
Eye/Ear Drops: 0.3% w/v

Pharmacopoeial Compliance: USP / IP / BP (as per client preference)
Available Packaging:
Alu-Alu or Blister for tablets
HDPE bottles for syrups and drops
Glass or plastic bottles with dropper caps for topical forms
Infusion bottles in FFS or glass packaging
Customized mono cartons with or without inserts

Pharmacodynamics and Mechanism of Action

Ciprofloxacin is a synthetic broad-spectrum fluoroquinolone that exerts its bactericidal effect by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication, repair, and transcription. This leads to the disruption of bacterial cell division and results in rapid bacterial death.

Ciprofloxacin demonstrates activity against a wide range of aerobic Gram-negative and some Gram-positive bacteria, and is particularly effective against urinary tract pathogens, respiratory bacteria, gastrointestinal infections, and skin/soft tissue organisms.

Antimicrobial Spectrum

Ciprofloxacin is effective against a variety of clinically relevant pathogens, including:
Escherichia coli
Klebsiella pneumoniae
Pseudomonas aeruginosa
Salmonella and Shigella spp.
Neisseria gonorrhoeae
Haemophilus influenzae
Proteus mirabilis
Enterobacter spp.
Legionella pneumophila
Staphylococcus aureus (including MSSA)

It is not effective against most anaerobic bacteria and is generally avoided in cases of streptococcal pharyngitis due to limited efficacy against Streptococcus pyogenes.

Therapeutic Indications

Ciprofloxacin is indicated for the treatment of infections caused by susceptible microorganisms. Commonly prescribed for:
Urinary tract infections, including cystitis and pyelonephritis
Lower and upper respiratory tract infections
Gastrointestinal infections (including typhoid fever, traveler’s diarrhea)
Bone and joint infections
Skin and soft tissue infections
Sexually transmitted infections (e.g., gonorrhea)
Infectious diarrhea
Febrile neutropenia (as part of combination therapy)
Prophylaxis against anthrax exposure
Post-surgical or catheter-associated infections

Dosage and Administration

Dosage depends on the type and severity of infection, patient weight, renal function, and formulation.

Adults:
250 mg to 750 mg orally every 12 hours
400 mg IV every 8–12 hours for severe infections

Pediatric (in select indications such as complicated UTI or anthrax):
10–20 mg/kg/dose every 12 hours, not exceeding adult dose

Eye/Ear Drops:
One or two drops every 2–4 hours depending on severity

Oral suspensions and pediatric dispersible tablets are available for age-specific dosage administration. Dosage adjustments are required in renal impairment cases.

Benefits of Ciprofloxacin

High oral bioavailability (approximately 70%)
Rapid onset of action and strong tissue penetration
Broad-spectrum coverage including Gram-negative pathogens
Effective against multidrug-resistant urinary and enteric bacteria
Available in oral, injectable, and topical dosage forms
Affordable and accessible therapy option in both urban and rural healthcare settings
Minimal cross-resistance with other antibiotic classes

Why Partner with BluepillExpress for Ciprofloxacin Manufacturing?

WHO-GMP and ISO Certified Manufacturing Plants
Our advanced manufacturing units comply with WHO-GMP, ISO 9001:2015, and other regulatory norms, ensuring premium quality across all dosage forms of Ciprofloxacin.

Formulation Flexibility and Customization
Whether you require Ciprofloxacin in tablet, suspension, drop, or injectable form, we provide:
Customized strengths and dosage forms
Flavor-masked oral solutions for pediatric use
Preservative-free options for sensitive products
Sachet or bottle-based reconstitution packs
Private label packaging and branding services

Global Export Experience
Our Ciprofloxacin products are exported to over 40 countries across:
Africa (Nigeria, Kenya, Ghana, Ethiopia)
Asia (Vietnam, Myanmar, India, Nepal)
Middle East (Iraq, UAE, Saudi Arabia)
Latin America (Peru, Ecuador, Guatemala)
CIS and Eastern Europe
We also offer export packaging customization, multilingual labeling, and region-specific regulatory documentation.

Comprehensive Regulatory and Dossier Support
We provide:
Certificate of Analysis (COA)
Certificate of Pharmaceutical Product (COPP)
Free Sale Certificate (FSC)
Stability Data (Real-Time & Accelerated)
Product Technical Dossier (CTD / ACTD)
Bioequivalence support documentation (for regulated markets)

Superior Quality Control Systems
BluepillExpress follows stringent in-process and finished product testing, including:
Active pharmaceutical ingredient assay and purity
Dissolution and disintegration profiling
Microbial limit testing
Sterility and particulate matter testing (for IV)
Reconstitution time and viscosity (for suspensions)
Packaging integrity testing

Packaging and Branding Solutions

BluepillExpress provides end-to-end packaging services that meet global expectations.
Tablet blister packs (PVC-Alu or Alu-Alu) in 10×10, 10×6, or 1×10 formats
Oral suspensions in HDPE/PET bottles with or without measuring cups
FFS infusion bottles or glass ampoules for IV use
Topical dropper bottles with tamper-evident caps
Custom-designed mono cartons and printed inserts
Private labeling for third-party brands with QR-coded authentication
Multilingual artwork design and compliance for international markets

Contract Manufacturing Process at BluepillExpress

We have streamlined our third-party and contract manufacturing process to ensure a seamless experience for our partners.

Step 1: Requirement Discussion and NDA
Detailed discussion on dosage forms, market preferences, and regulatory scope, followed by a Non-Disclosure Agreement.

Step 2: Pricing and Product Finalization
Product strength, dosage, and packaging configurations are finalized. Commercial quote and batch size are shared.

Step 3: Sample Development and Approval
Pilot batch is developed and shared for review. Any customizations required are incorporated.

Step 4: Commercial Manufacturing
On approval, full-scale manufacturing is initiated. Each batch is tested and documented according to compliance standards.

Step 5: Delivery and Documentation
Final goods are packed as per client specifications and dispatched with all necessary documents for registration, import, and sale.

Ciprofloxacin in the Global Market

Ciprofloxacin continues to be among the top-prescribed antibiotics worldwide, particularly in countries with high burdens of urinary and enteric infections. It features on the WHO Essential Medicines List and is widely distributed via national health programs, NGOs, private hospitals, and pharmacies.

With increasing awareness about antimicrobial stewardship, there is high demand for quality-assured generics with proper packaging, branding, and compliance documentation—exactly what BluepillExpress offers.

Target Clients and Use Cases

Pharmaceutical marketing companies looking to expand their antibacterial portfolio
Government agencies procuring for national essential drug programs
NGOs and relief organizations operating in infectious disease zones
Hospital suppliers and tenders
Retail pharmacy distributors in Africa, Asia, CIS, and Latin America
Companies looking for private label Ciprofloxacin under their brand

Whether you are a startup entering the antibiotic space or an established distributor expanding your catalog, Ciprofloxacin from BluepillExpress ensures market trust, therapeutic reliability, and strong commercial viability.

Conclusion

Ciprofloxacin remains a powerful, reliable, and globally accepted antibiotic for a wide spectrum of infections. Its affordability, versatility, and broad-spectrum activity make it a must-have product in every pharmaceutical company’s offering.

As your trusted third-party manufacturing partner, BluepillExpress offers Ciprofloxacin in multiple dosage forms and strengths, backed by certified facilities, proven documentation, and global export readiness. We ensure consistent product performance, timely delivery, and scalable production that helps you meet growing demand in every market you serve.