Ceftriaxone 500mg & Tazobactam 62.5 mg

In the era of rising antimicrobial resistance and evolving bacterial infections, healthcare providers require potent, broad-spectrum antibiotic combinations that deliver rapid, effective, and safe results. Ceftriaxone 500 mg & Tazobactam 62.5 mg is one such synergistic antimicrobial formulation designed to combat severe infections caused by beta-lactamase producing organisms. As an internationally recognized pharmaceutical manufacturer and exporter, BluepillExpress provides third-party manufacturing solutions for this critical drug, ensuring quality, compliance, and global standards are met.

With our WHO-GMP certified infrastructure, regulatory expertise, and global reach, we are your trusted partner for manufacturing Ceftriaxone & Tazobactam injectable formulations that are safe, stable, and therapeutically effective. Our manufacturing services are tailored to meet the needs of pharmaceutical companies, hospital suppliers, distributors, and global importers.

About BluepillExpress

BluepillExpress is a leading pharmaceutical manufacturer and global exporter, offering comprehensive third-party and contract manufacturing services for a wide range of therapeutic segments. With a presence in over 30 countries, including Africa, Southeast Asia, the Middle East, and CIS regions, we provide end-to-end pharmaceutical solutions—ranging from formulation development to packaging and global dispatch.

Our manufacturing units are certified under WHO-GMP, ISO 9001:2015, and FSSAI, ensuring international regulatory compliance, safety, and quality. We specialize in sterile injectable formulations, including Ceftriaxone 500 mg with Tazobactam 62.5 mg, and other beta-lactam antibiotic combinations.

Product Overview: Ceftriaxone 500 mg & Tazobactam 62.5 mg

Ceftriaxone, a third-generation cephalosporin, is known for its broad-spectrum activity against both Gram-positive and Gram-negative bacteria. Tazobactam, a beta-lactamase inhibitor, enhances the effectiveness of ceftriaxone by inhibiting beta-lactamase enzymes that bacteria produce to resist antibiotic action.

This combination extends the antibacterial spectrum and is particularly effective against beta-lactamase-producing pathogens, making it highly suitable for empirical therapy in severe infections.

Composition

• Ceftriaxone Sodium Equivalent to Ceftriaxone – 500 mg
• Tazobactam Sodium Equivalent to Tazobactam – 62.5 mg

Mechanism of Action

• Ceftriaxone inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and death.
• Tazobactam irreversibly binds to bacterial beta-lactamase enzymes, preventing the degradation of ceftriaxone and restoring its antibacterial efficacy.

Therapeutic Indications

The combination of Ceftriaxone 500 mg & Tazobactam 62.5 mg is indicated for the treatment of a wide range of infections, including:

• Lower Respiratory Tract Infections (e.g., pneumonia, bronchitis)
• Urinary Tract Infections (e.g., complicated and uncomplicated UTIs)
• Intra-abdominal Infections
• Skin and Soft Tissue Infections
• Gynecological Infections
• Bone and Joint Infections
• Septicemia and Bacteremia
• Post-operative Infections
• Hospital-Acquired Infections

Dosage and Administration

• Administered via intravenous (IV) or intramuscular (IM) injection.
• Dosage and duration depend on the type and severity of infection and patient response.
• Reconstituted using sterile water for injection before administration.
• Compatibility and dilution guidelines are provided in the packaging insert.

Key Benefits

• Broad-spectrum antibacterial activity with enhanced beta-lactamase inhibition
• Single daily dosing for convenience and compliance
• Effective in treating multi-drug resistant infections
• Stable in aqueous solution for safe reconstitution
• Rapid onset of action with high tissue penetration
• Supported by global clinical evidence and usage

Manufacturing Excellence at BluepillExpress

Our injectable formulation units meet the highest international standards for sterility, quality, and process control:

• Sterile Manufacturing Environment: Class 100 cleanrooms with HEPA filtration
• Aseptic Processing: Advanced filling, sealing, and lyophilization lines
• Validated Equipment: Auto-claves, depyrogenation tunnels, and sterile filtration systems
• Batch Production Records: Maintained digitally for traceability and compliance
• Stability Testing: Conducted as per ICH guidelines for all injectable batches

Packaging Options

BluepillExpress offers customizable packaging solutions to meet regulatory and commercial requirements:

• Glass Vials (Type I or Type II)
• Flip-off or Tear-off Aluminum Seals
• Sterile Water for Injection (SWFI) Ampoule or Vial included (optional)
• Outer Monocarton Packaging with multilingual labeling
• Pack Sizes: Single vial, vial with WFI ampoule, or hospital packs
• Tamper-evident seals and barcoding as per client specifications

Quality Control and Quality Assurance

BluepillExpress maintains stringent quality protocols in accordance with WHO-GMP and ISO requirements:

• Raw Material Testing: Every API and excipient is verified for identity, purity, and potency
• In-Process Testing: pH, reconstitution time, fill volume, particulate matter, and sterility tests
• Finished Product Testing: Assay, dissolution, microbial load, pyrogen, and endotoxin testing
• Stability Testing: Conducted under real-time and accelerated conditions
• Documentation: Batch Manufacturing Records (BMR), Certificate of Analysis (CoA), and Sterility Certificates provided with each batch

Regulatory Support and Export Documentation

As a global exporter, BluepillExpress provides complete regulatory and technical documentation required for product registration in various international markets:

• Certificate of Pharmaceutical Product (COPP)
• Certificate of Analysis (CoA)
• Certificate of Origin
• GMP Certificate
• Product Dossier (CTD/ACTD format)
• Stability Reports and Validation Data
• MSDS (Material Safety Data Sheet)
• Label and Artwork Assistance

Private Label and Custom Branding

BluepillExpress offers full private label manufacturing services for pharmaceutical companies looking to expand their injectable antibiotic range. We provide:

• Custom logo and label printing
• Artwork development as per regional regulations
• Country-specific regulatory compliance for branding
• White-label solutions for hospital and institutional supply

Global Supply and Logistics

Our well-established logistics network ensures smooth delivery and compliance with international shipping standards:

• Temperature-controlled transportation if required
• Tamper-proof export packaging
• Sea, air, and courier freight support
• Country-specific export documentation
• Cold chain management for sensitive APIs

Who Can Partner with Us?

• Pharmaceutical Marketing Companies
• Hospital Suppliers and Distributors
• Government Health Tender Participants
• International Importers & Wholesalers
• NGOs and Public Health Projects
• Generic Pharmaceutical Brands

Why Choose BluepillExpress?

• WHO-GMP & ISO Certified Infrastructure
• Experience in Sterile Injectable Manufacturing
• Regulatory Documentation Support for Over 30 Countries
• Low MOQ Flexibility for Emerging Brands
• On-Time Delivery and Scalable Production
• 100% Confidentiality and IP Protection
• Competitive Pricing with Quality Assurance

Conclusion

The combination of Ceftriaxone 500 mg and Tazobactam 62.5 mg is a potent antimicrobial solution that addresses the rising need for broad-spectrum antibiotic therapy. At BluepillExpress, we are committed to manufacturing this vital formulation with the utmost precision, quality, and safety. With our robust manufacturing capacity, global regulatory expertise, and end-to-end support, we empower pharmaceutical businesses to bring effective infection control solutions to their markets.

Partner with BluepillExpress for third-party manufacturing of Ceftriaxone & Tazobactam injection—where trust, quality, and compliance come together to deliver therapeutic excellence.