Cefoperazone & Sulbactam

Cefoperazone and Sulbactam is a powerful combination antibiotic therapy that has proven efficacy against a wide range of gram-positive and gram-negative bacterial infections, including beta-lactamase producing organisms. This synergistic formulation plays a crucial role in treating complicated infections in both hospital and outpatient settings.

At BluepillExpress, we offer third-party manufacturing of high-quality Cefoperazone & Sulbactam formulations under stringent regulatory standards. As a globally recognized pharmaceutical manufacturer and exporter, we specialize in contract manufacturing services for this critically important antimicrobial combination, ensuring GMP-compliant production, global export readiness, and superior quality assurance.

Whether you’re a pharmaceutical distributor, healthcare brand, or international importer, BluepillExpress is your reliable partner for customized, scalable, and globally certified manufacturing of Cefoperazone & Sulbactam products.

About Cefoperazone & Sulbactam

Cefoperazone is a third-generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. It works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. However, the growing threat of beta-lactamase-producing bacteria reduces its effectiveness in some infections.

Sulbactam is a beta-lactamase inhibitor that has minimal intrinsic antibacterial activity but significantly enhances the efficacy of Cefoperazone by inhibiting beta-lactamase enzymes. The combination provides robust coverage against resistant strains, making it effective in managing complicated intra-abdominal, respiratory, urinary tract, skin, and soft tissue infections.

This dual-action combination is especially valuable in the empirical treatment of hospital-acquired infections (HAIs), where multi-drug-resistant organisms are prevalent.

BluepillExpress: Your Strategic Manufacturing Partner

BluepillExpress offers world-class third-party manufacturing services for Cefoperazone & Sulbactam in multiple forms. Our manufacturing facility is WHO-GMP certified, ISO-compliant, and equipped with advanced production systems to ensure the integrity, potency, and sterility of each batch.

Our Cefoperazone & Sulbactam manufacturing offerings include:

• Cefoperazone 1000 mg + Sulbactam 500 mg for Injection
• Cefoperazone 1000 mg + Sulbactam 1000 mg for Injection
• Customized strengths as per regulatory requirement or tender specifications

We provide sterile dry powder injections packed in vials, ampoules for diluents, flip-off seals, and high-quality cartons suitable for both private label and white-label clients.

Therapeutic Uses and Indications

Cefoperazone & Sulbactam combination is indicated in the treatment of:

• Lower Respiratory Tract Infections including pneumonia and bronchitis
• Urinary Tract Infections, both complicated and uncomplicated
• Intra-abdominal Infections such as peritonitis
• Septicemia and Bacteremia
• Skin and Soft Tissue Infections
• Pelvic Inflammatory Disease (PID)
• Post-surgical Infections
• Bone and Joint Infections

The combination is often used in intensive care units (ICUs) and post-operative settings to combat infections where resistant pathogens are suspected or confirmed.

Manufacturing Excellence at BluepillExpress

At BluepillExpress, quality, precision, and compliance define our manufacturing process. Our sterile injection manufacturing units are equipped with cutting-edge technology and certified cleanrooms to support the production of high-potency, parenteral antibiotics.

Key Manufacturing Features:

• WHO-GMP Certified Facility
• Sterile Dry Powder Filling with automatic vial washers and autoclaves
• Automated Manufacturing Lines with integrated cleanroom systems (Class 100 / ISO 5)
• Validated Aseptic Processing Protocols
• HEPA-filtered air systems and pressure-differentiated zones
• Batch segregation and traceability system for quality assurance

We strictly follow Good Manufacturing Practices (GMP) as per WHO and international guidelines to ensure every batch is sterile, safe, and effective.

Composition and Formulation Flexibility

We offer formulation flexibility to cater to different country-specific regulatory and therapeutic needs:

• Cefoperazone Sodium 1000 mg + Sulbactam Sodium 500 mg
• Cefoperazone Sodium 1000 mg + Sulbactam Sodium 1000 mg
• Dual-chamber vial system (optional for specialized markets)
• Vial + Ampoule Kits with diluents (water for injection)
• Glass vials with rubber stoppers, flip-off seals, and custom labeling

All raw materials used in the formulation are sourced from GMP-certified API manufacturers and undergo strict quality evaluation.

Quality Control and Testing

BluepillExpress has a dedicated in-house quality control and quality assurance department with highly trained microbiologists, chemists, and analysts.

Quality Checks Include:

• Assay and potency testing
• Sterility and pyrogen testing
• pH level validation
• Endotoxin testing
• Particle size and reconstitution time checks
• Compatibility and stability studies

Each batch is issued with a Certificate of Analysis (COA) and can be accompanied by MSDS, stability data, and third-party validation reports if required.

Packaging and Customization

We offer multiple packaging options to suit private label, institutional, and export needs:

• Glass Vials in 10 ml and 20 ml sizes
• Custom Branded Cartons
• Single and Dual Ampoule Systems
• Customized Labeling with QR Code/Barcode Integration
• Export Packaging with multilingual instructions and tamper-proof seals

All packaging is done in controlled environments using pharma-grade materials, with special attention to light and moisture resistance to maintain product stability.

Regulatory and Documentation Support

BluepillExpress supports your brand with comprehensive regulatory documentation, including:

• WHO-GMP and ISO 9001:2015 Certificates
• FSSAI License (for relevant products)
• Certificate of Analysis (COA)
• Certificate of Pharmaceutical Product (COPP)
• Certificate of Origin (COO)
• Free Sale Certificate (FSC)
• Stability Reports (Real-time and Accelerated)
• Master Formula Record (MFR) and Batch Manufacturing Record (BMR)

We also assist with dossier preparation for registration in international markets, including submission files compliant with USFDA, TGA, MHRA, and ANVISA guidelines, depending on the client’s market requirement.

Private Label & White Label Solutions

BluepillExpress makes it easy for you to launch your own brand of Cefoperazone & Sulbactam. Our private label services include:

• Custom brand name selection
• Logo and label design
• Regulatory guidance
• Product prototypes for sampling and approval
• MOQ flexibility for emerging brands and international startups
• White-label-ready inventory for urgent delivery

We maintain strict confidentiality agreements (NDA) and ensure intellectual property protection across all stages of development and production.

Export Capability

BluepillExpress is a leading exporter of Cefoperazone & Sulbactam injections to more than 30 countries, including:

• Africa: Nigeria, Kenya, Ghana, Ethiopia
• Southeast Asia: Vietnam, Philippines, Cambodia
• Middle East: UAE, Iraq, Saudi Arabia
• CIS Countries: Uzbekistan, Kazakhstan
• Latin America: Peru, Ecuador, Bolivia
• South Asia: Sri Lanka, Nepal, Bangladesh

We ensure end-to-end export compliance including:

• Custom clearance coordination
• Air and sea freight arrangements
• WHO Prequalification (PQ) support for eligible markets
• Packaging, documentation, and transport validation

Minimum Order Quantities (MOQs)

We offer competitive and flexible MOQ structures for:

• Institutional Supply and Government Tenders
• Private Label Launches
• Export Contracts
• Local Wholesale Distribution

MOQs can be adjusted based on formulation complexity, regulatory requirements, and packaging preferences.

Why Choose BluepillExpress?

• GMP-certified facility with advanced injectable manufacturing technology
• Uncompromising quality assurance and global regulatory compliance
• End-to-end support from R&D to dispatch
• Client-first approach with transparent pricing and delivery schedules
• Dedicated export documentation and regulatory teams
• Customizable solutions for every type of client—distributors, hospitals, tender suppliers, and brands

We bring years of pharmaceutical expertise, global supply experience, and manufacturing excellence to ensure your Cefoperazone & Sulbactam products meet the highest clinical and commercial standards.

Testimonials

“BluepillExpress helped us enter the injectable antibiotics market with a reliable and well-packaged Cefoperazone & Sulbactam product. Their manufacturing and export support is top-tier.”
— Pharmaceutical Distributor, Kenya

“From batch sampling to registration documents, the BluepillExpress team handled everything smoothly. We are now expanding our antibiotic range with them.”
— Regulatory Manager, Middle East

“Their sterile injection plant is impressive. We’ve placed repeated orders due to consistent product quality and timely deliveries.”
— Procurement Head, Hospital Chain – India

Conclusion

Cefoperazone & Sulbactam remains a critical component in the global fight against bacterial infections and antibiotic resistance. As a combination therapy with clinical superiority, demand for this product continues to grow in both public and private healthcare sectors.

BluepillExpress is proud to offer third-party manufacturing services for Cefoperazone & Sulbactam that adhere to the highest standards of safety, efficacy, and compliance. Whether you need bulk manufacturing, private label solutions, or export-ready injectable products, we are your trusted pharmaceutical partner.