Cefixime

The global burden of bacterial infections continues to rise, with an increasing need for potent, well-tolerated, and broad-spectrum antibiotics. Cefixime, a third-generation oral cephalosporin, has proven efficacy against a wide variety of Gram-positive and Gram-negative pathogens, making it a first-choice therapy for numerous community-acquired infections.

BluepillExpress, a globally recognized pharmaceutical manufacturer and exporter, offers reliable and scalable third-party manufacturing services for Cefixime. Whether your brand targets domestic healthcare providers, export markets, or institutional supply chains, BluepillExpress delivers international-grade Cefixime formulations with assured quality, documentation support, and global compliance.

Product Overview

Generic Name: Cefixime
Dosage Forms Available:

• Cefixime Tablets
• Cefixime Dispersible Tablets
• Cefixime Capsules
• Cefixime Dry Syrup (For pediatric use)
• Cefixime Oral Suspension

Strengths Available:

• 50 mg / 100 mg / 200 mg / 400 mg tablets or capsules
• 50 mg/5ml or 100 mg/5ml dry syrup formulations

Therapeutic Category: Third-Generation Cephalosporin Antibiotic
Pharmacopoeial Standard: USP / IP / BP available upon request
Packaging Options: Blister packs, alu-alu packs, bottles (for syrups), cartons with inserts

Pharmacological Profile

Cefixime is a broad-spectrum cephalosporin antibiotic that belongs to the third-generation class. It works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), leading to cell lysis and death. It has excellent oral bioavailability and is highly stable to hydrolysis by most beta-lactamases.

Antibacterial Spectrum:

Cefixime is effective against the following organisms:

Gram-positive bacteria:

• Streptococcus pneumoniae
• Streptococcus pyogenes

Gram-negative bacteria:

• Haemophilus influenzae
• Escherichia coli
• Proteus mirabilis
• Neisseria gonorrhoeae
• Salmonella and Shigella species
• Klebsiella pneumoniae

Indications

Cefixime is indicated for the treatment of a wide range of infections, including:

• Upper respiratory tract infections (URTI): pharyngitis, tonsillitis
• Lower respiratory tract infections (LRTI): bronchitis, mild pneumonia
• Otitis media
• Urinary tract infections (UTIs): cystitis, pyelonephritis
• Sexually transmitted infections: uncomplicated gonorrhea
• Typhoid fever and enteric infections
• Acute bacterial sinusitis
• Skin and soft tissue infections (SSTIs)
• Pediatric infections in syrup form

Dosage and Administration

Dosage of Cefixime depends on the indication, age, renal function, and clinical condition of the patient.

Adults and Adolescents (12 years and older):

• Usual dose: 200 mg to 400 mg daily, either as a single dose or divided into two doses of 200 mg every 12 hours.

Children (6 months to 12 years):

• 8 mg/kg/day administered in one or two divided doses
• Syrup and suspension forms available for pediatric use

Renal Impairment:

• Dose adjustment recommended for patients with significantly impaired renal function.

Route of Administration:

• Oral (tablet, dispersible tablet, capsule, or reconstituted syrup)

Why Choose BluepillExpress for Third-Party Manufacturing of Cefixime?

1. WHO-GMP and ISO Certified Facilities

Our manufacturing facilities are compliant with WHO-GMP and ISO 9001:2015 standards, ensuring that every batch of Cefixime meets global regulatory and quality norms.

2. Flexible Dosage and Packaging Solutions

We offer a wide range of Cefixime dosage forms and strengths with multiple packaging options:

• Blister (PVC/Alu or Alu/Alu)
• Bottles with childproof caps (for syrups)
• Custom branding, language-specific labeling, and private-label packaging

3. Global Documentation and Regulatory Support

Our regulatory support team provides:

• Certificate of Analysis (COA)
• Certificate of Pharmaceutical Product (COPP)
• Free Sale Certificate (FSC)
• Stability data (real-time and accelerated)
• Technical Dossier (CTD/ACTD)
• Product Registration Support for various global markets

4. Export Expertise Across Continents

We export Cefixime products to:

• Africa (Nigeria, Kenya, Ghana, Tanzania, Ethiopia)
• Southeast Asia (Vietnam, Philippines, Cambodia, Myanmar)
• Latin America (Peru, Bolivia, Colombia)
• Middle East (Yemen, Iraq, Jordan, UAE)
• CIS & Central Asia (Uzbekistan, Kyrgyzstan, Kazakhstan)
• Regulatory-ready solutions for UK, EU, and semi-regulated markets

Quality Control and Assurance

Every batch of Cefixime manufactured by BluepillExpress undergoes stringent quality checks and complies with pharmacopeial standards.

Key Testing Parameters:

• API Assay and Identification
• Uniformity of Dosage Units
• Microbial Load and Stability
• Dissolution and Disintegration
• Content Uniformity
• pH and Viscosity (for syrups)

Our in-house QC labs and qualified analysts ensure that only compliant, stable, and effective products reach your end customers.

Contract Manufacturing Process

We follow a streamlined and transparent process for our contract manufacturing services:

Step 1: Requirement Assessment

We understand your brand’s market needs, dosage preferences, and regulatory landscape.

Step 2: NDA and Formulation Discussion

Non-disclosure agreement signed. Formulation is finalized based on your specifications and target audience.

Step 3: Sampling and Costing

Pilot samples are created and shared for approval, along with competitive pricing and minimum order quantities.

Step 4: Commercial Production

Bulk production is initiated after approvals. All processes are documented with batch-wise traceability.

Step 5: Packaging and Delivery

Final products are packed as per client instructions and shipped with complete documentation for domestic or export use.

Product Customization Options

To help your brand stand out in the competitive antibiotic market, we offer customized solutions, such as:

• Flavored dispersible tablets (orange, banana, strawberry)
• Sugar-free syrup for diabetic or calorie-conscious patients
• Pediatric-friendly dosing syrups with measuring spoons
• Multilingual carton printing (Arabic, French, Spanish, Russian, etc.)
• QR-coded labels for supply chain verification and track-and-trace compliance

Market Demand and Commercial Scope

Cefixime is listed in WHO’s Essential Medicines List and is widely used in both public and private healthcare sectors. It is also included in national guidelines for the treatment of typhoid, STIs, and pediatric infections. The global antibiotic market is valued in billions of dollars, and Cefixime continues to command significant prescription volumes due to:

• Broad-spectrum coverage
• Oral convenience
• Cost-effective treatment option
• Suitable for pediatric and geriatric populations
• Minimal resistance in most regions

Opportunities for Distributors, Hospitals, and Generic Brands

BluepillExpress supports:

• Distributors in regulated and semi-regulated markets
• Retail pharmacy chains and hospitals
• Government tender suppliers
• Private-label brand owners
• NGOs and international health organizations

Whether you are an emerging business looking to launch your first antibiotic, or an established healthcare group expanding your antimicrobial portfolio, BluepillExpress provides scalable solutions to grow your presence in the pharmaceutical sector.

Scientific and Clinical References

Cefixime has been studied extensively in clinical trials for its efficacy in:

• Typhoid fever management
• Uncomplicated gonorrhea
• Pediatric otitis media
• Upper and lower respiratory tract infections
• Community-acquired urinary infections

The drug has demonstrated a favorable safety profile, with side effects limited to mild gastrointestinal disturbances in most cases. It remains one of the most prescribed oral cephalosporins in both primary and secondary healthcare settings.

Conclusion

Cefixime is a time-tested, highly effective oral antibiotic that continues to play a central role in treating a wide range of infections across all age groups. With the global demand for quality, affordable antibiotics continuing to grow, launching your own Cefixime brand is a strategic investment for long-term business growth.

BluepillExpress is your dependable partner in manufacturing Cefixime with international quality standards, regulatory readiness, and export compliance. Our infrastructure, documentation capabilities, and commitment to excellence make us a preferred third-party manufacturer for clients worldwide.