Cefadroxil

Cefadroxil is a first-generation cephalosporin antibiotic that is widely used in the treatment of a variety of bacterial infections. Known for its broad-spectrum activity and excellent oral absorption, Cefadroxil is effective against both Gram-positive and select Gram-negative bacteria. It is structurally and pharmacologically related to other cephalosporins, and it acts by disrupting bacterial cell wall synthesis, resulting in the elimination of the pathogen.

As a reliable and effective antibacterial agent, Cefadroxil is commonly prescribed for respiratory tract infections, urinary tract infections, skin and soft tissue infections, and pharyngitis/tonsillitis. With increasing global demand for high-quality antibiotic formulations, BluepillExpress proudly offers contract and third-party manufacturing of Cefadroxil in multiple dosage forms and strengths.

Our commitment to compliance, consistent quality, and scalability enables our clients to bring their antibiotic brands to market confidently, both domestically and internationally.

Therapeutic Uses of Cefadroxil

Cefadroxil is primarily prescribed for treating bacterial infections such as:

• Upper and lower respiratory tract infections including bronchitis and pneumonia
• Pharyngitis and tonsillitis caused by Streptococcus pyogenes
• Urinary tract infections including cystitis and pyelonephritis
• Skin and soft tissue infections, including cellulitis, impetigo, and wound infections
• Bone infections in certain clinical cases

Its excellent bioavailability and tolerability profile make it suitable for both adult and pediatric use.

Mechanism of Action

Cefadroxil is a bactericidal antibiotic that inhibits the final stage of bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs), thereby preventing peptidoglycan cross-linking within the bacterial cell wall. This leads to the weakening and rupture of the cell wall, resulting in bacterial cell death.

Its activity is most potent against Gram-positive cocci such as Streptococcus pneumoniae, Staphylococcus aureus (non-MRSA), and some Gram-negative organisms including Escherichia coli, Proteus mirabilis, and Klebsiella pneumoniae.

Available Dosage Forms at BluepillExpress

At BluepillExpress, we manufacture Cefadroxil in a variety of dosage forms tailored to different market segments and regulatory requirements:

1. Cefadroxil Tablets and Capsules

• 250 mg
• 500 mg
• 1 g

2. Cefadroxil Oral Suspension (for pediatric use)

• 125 mg/5 ml
• 250 mg/5 ml

3. Cefadroxil Dry Syrup (Reconstitution Required)

• Customizable per pediatric dosage needs

Each dosage form is developed with strict adherence to pharmacopeial standards such as BP, USP, or IP, as per client specification.

Why Partner with BluepillExpress for Cefadroxil Manufacturing?

As an established third-party manufacturer and exporter of pharmaceutical formulations, BluepillExpress offers a comprehensive range of services to meet your product goals in the most efficient, compliant, and scalable manner. Here’s what sets us apart:

1. WHO-GMP Certified Manufacturing Units

Our facilities are built to comply with WHO-GMP, ISO 9001:2015, ISO 14001, and FSSAI guidelines, ensuring global-quality pharmaceutical manufacturing with consistency, safety, and precision.

2. Advanced Manufacturing Infrastructure

• High-speed tablet compression and capsule filling lines
• Dedicated dry syrup production zones
• Cleanroom processing and packaging areas
• In-house analytical labs and microbiological labs
• Automated blister and bottle packing machines

3. Custom Formulation and Packaging

We offer formulation and packaging customization to suit your branding and regional market needs, including:

• Film-coated, sugar-coated, and uncoated tablets
• Blister packs, strip packs, HDPE bottles
• Pediatric-friendly flavorings for suspensions (orange, strawberry, etc.)
• Private labeling with logo and regulatory-compliant packaging artwork

4. Extensive Quality Control and Quality Assurance

We ensure thorough in-process and finished product testing, including:

• Assay and content uniformity
• Dissolution and disintegration testing
• Microbial limit testing
• Stability studies under ICH guidelines
• Shelf-life extension and real-time stability data

Regulatory Support and Documentation

BluepillExpress supports clients in achieving seamless regulatory compliance for domestic as well as international markets. We provide full documentation and certification support, including:

• Certificate of Analysis (COA)
• Batch Manufacturing Record (BMR)
• Master Formula Record (MFR)
• Product Development Report
• Technical Data Sheet (TDS)
• Material Safety Data Sheet (MSDS)
• Stability Data
• Dossiers in CTD or ACTD format for product registration

Whether you’re launching your brand in India, Africa, the Middle East, Southeast Asia, or Latin America, we ensure a compliant and smooth registration process.

Global Export Capabilities

BluepillExpress has built a strong network as a global exporter of antibiotic formulations, currently serving over 40 countries through a combination of distributor partnerships, institutional contracts, and retail brand development.

We have extensive experience in shipping and registering Cefadroxil products in countries including:

• Nigeria, Ghana, Kenya, and South Africa
• UAE, Saudi Arabia, and Oman
• Bangladesh, Vietnam, and the Philippines
• Colombia, Peru, and Dominican Republic
• CIS countries such as Uzbekistan and Kazakhstan

Our export support team assists with:

• Label translations
• Local language packaging
• Country-specific documentation
• Cold chain and ambient shipping conditions

Private Labeling and Custom Branding

We offer comprehensive private label solutions to allow your brand to expand its antibiotic portfolio with ease. Services include:

• Logo and brand identity creation
• Custom carton and label printing
• Market-specific SKU generation
• E-commerce-friendly packaging
• Sample development and visual mockups

This end-to-end service makes BluepillExpress an ideal partner for startups and established pharmaceutical brands alike.

Research and Development

Our R&D division continuously works to enhance:

• Bioavailability through innovative granulation and particle sizing
• Palatability for pediatric suspensions
• Stability under high humidity and tropical conditions
• Combination products (e.g., Cefadroxil with Clavulanic Acid, or anti-inflammatory agents)
• Alternative dosage forms such as dispersible tablets and sachets

We also provide formulation feasibility studies and support product differentiation strategies for competitive positioning in your target markets.

Shelf Life and Storage

• Shelf Life: 24 to 36 months based on dosage form and packaging
• Storage Conditions: Store in a dry place below 25°C, protect from moisture and light
• Pediatric suspensions must be used within 7 to 10 days after reconstitution

Our packaging is designed to ensure stability and extended shelf life even in Zone III and IV countries, making it suitable for tropical climates.

Environmental Responsibility and Safety

We are committed to environmental stewardship and regulatory compliance in all aspects of our operations:

• Effluent treatment systems (ETP) and waste segregation
• Responsible disposal of beta-lactam waste materials
• Use of eco-friendly packaging options
• Employee training on GMP, safety, and hygiene protocols
• Risk assessment and audit practices for continual improvement

Conclusion

Cefadroxil remains a reliable and effective antibiotic for treating a variety of bacterial infections, offering both safety and efficacy across all age groups. With its proven clinical record, it continues to be in high demand in both developed and developing healthcare markets.

At BluepillExpress, we offer reliable third-party manufacturing solutions for Cefadroxil—designed with precision, manufactured under stringent standards, and ready for global distribution. Whether you’re looking to expand your product portfolio, enter new markets, or require a dependable manufacturing partner, we are here to support your business at every step.