Tetramisole HCL

Tetramisole Hydrochloride (HCl) is a broad-spectrum anthelmintic agent used in the treatment of gastrointestinal worm infestations in humans and animals. It is especially effective against Ascaris lumbricoides (roundworm), hookworms, and other nematodes by interfering with neuromuscular transmission in the parasites. Additionally, it has demonstrated immunomodulatory properties, further enhancing its value in therapeutic protocols.

As an essential drug in public health deworming campaigns, veterinary practice, and endemic regions, Tetramisole HCl remains in high demand. Its affordability, quick action, and versatility have made it a staple in both human and veterinary medicine.

At BluepillExpress, we are proud to offer high-quality, WHO-GMP-certified third-party manufacturing services for Tetramisole Hydrochloride across multiple dosage forms. Our services cater to pharmaceutical companies, NGOs, government agencies, and veterinary health suppliers worldwide.

About BluepillExpress

BluepillExpress is a leading Indian pharmaceutical contract manufacturer with specialization in anthelmintic, anti-parasitic, and gastrointestinal drugs. With certified production facilities, deep industry expertise, and global reach, we support our clients with:

• WHO-GMP certified manufacturing
• Flexible MOQs for commercial and institutional orders
• Regulatory dossier preparation and documentation
• Private labeling and custom packaging
• Global logistics, export clearance, and on-time shipping

Our commitment to quality, scalability, and partnership makes us the preferred choice for organizations seeking reliable third-party manufacturing of Tetramisole HCl and other essential medicines.

Pharmacological Overview

• Generic Name: Tetramisole Hydrochloride
• Pharmacological Class: Anthelmintic
• Mechanism of Action: Paralysis of nematodes via ganglionic stimulation
• Route of Administration: Oral
• Formulations Offered: Tablets, Suspension (Human and Veterinary)

Mechanism of Action

Tetramisole HCl acts primarily as a depolarizing neuromuscular blocking agent in parasitic worms. It stimulates the parasympathetic ganglia and cholinergic receptors of the nematodes, leading to continuous muscle contraction and eventual paralysis. This causes the worms to lose their grip on the intestinal walls and be expelled naturally via peristalsis.

Additionally, Tetramisole has been studied for its immunomodulatory activity, as it boosts the host’s resistance by enhancing T-cell function, particularly in immunocompromised patients or animals.

Therapeutic Indications

Tetramisole Hydrochloride is indicated for the treatment of various helminthic infections, including:

In Humans:

• Ascariasis (roundworm infection)
• Hookworm infections
• Mixed worm infestations
• Adjuvant therapy in immunodeficient patients (off-label in some regions)

In Veterinary Medicine:

• Gastrointestinal nematode infections in livestock (e.g., sheep, goats, cattle)
• Lungworm infestations
• Deworming programs in poultry and companion animals

Its quick onset, low toxicity, and wide spectrum of activity make it ideal for mass deworming programs and routine prophylactic use.

Dosage Forms and Strengths Manufactured by BluepillExpress

BluepillExpress offers WHO-compliant manufacturing of Tetramisole HCl in multiple formulations, both for human pharmaceutical and veterinary use.

1. Tetramisole HCl Tablets (Human Use)

• Strengths: 50 mg, 150 mg
• Form: Uncoated or film-coated tablets
• Packaging: Blister packs (10×10), strips, HDPE bottles
• Shelf Life: 36 months
• Standards: IP/BP/USP

2. Tetramisole HCl Oral Suspension (Human Use)

• Strength: 30 mg/5 ml or 60 mg/5 ml
• Form: Flavored oral liquid
• Packaging: 30 ml / 60 ml / 100 ml bottles
• Features: Sugar-free, child-friendly formulas available

3. Tetramisole HCl Tablets (Veterinary Use)

• Strengths: 600 mg, 1000 mg
• Form: Bolus tablets for livestock
• Packaging: Strip packs, bottles, or bulk jars
• Labeling: Veterinary use only, with species-specific instructions

4. Tetramisole HCl Liquid Suspension (Veterinary Use)

• Strength: 10% or 15% w/v
• Use: Oral administration for cattle, sheep, goats, and poultry
• Packaging: 500 ml, 1 L, or 5 L plastic containers

Custom strengths and packaging are also available upon request.

Manufacturing Facility Overview

BluepillExpress operates a modern, WHO-GMP-certified pharmaceutical manufacturing facility equipped with precision machinery for both solid oral dosage forms and liquid formulations.

Key Capabilities:

• High-speed tablet compression and coating lines
• Automated liquid filling and sealing units
• Dedicated veterinary production zones
• Cleanroom environment with HEPA filtration
• On-site water purification and HVAC systems
• In-house R&D and quality control laboratories
• Temperature-controlled warehousing and dispatch zones

Our production lines can accommodate both large-scale supply contracts and small custom batches for new product launches or local market testing.

Quality Assurance and Quality Control

Our in-house Quality Management System (QMS) ensures that each batch of Tetramisole HCl complies with pharmacopoeial standards and is traceable from raw material to dispatch.

Key Quality Tests:

• API assay and purity analysis (HPLC/UV)
• Tablet disintegration and dissolution tests
• Microbial limit and sterility tests (liquids)
• Hardness, friability, and weight uniformity checks
• Accelerated and real-time stability testing
• Homogeneity and pH checks for oral suspensions

Documentation Provided:

• Certificate of Analysis (COA)
• Batch Manufacturing Records (BMR)
• Raw Material and Packaging Specifications
• Stability Data Reports
• MSDS and Product Dossier (on request)

All testing complies with IP, BP, or USP as per your target market requirements.

Packaging and Labeling Options

We offer a wide range of private-label packaging options suitable for retail, institutional, and veterinary markets.

For Human Use:

• Tablets: Alu-Alu or PVC/Alu blisters, strips, HDPE bottles
• Suspension: Amber or white HDPE bottles with tamper-evident caps
• Cartons with printed inserts in local/regional languages
• Barcoded packaging with serialization for traceability

For Veterinary Use:

• Tablets: Strip packs or jars for field distribution
• Suspension: Plastic or HDPE bottles, bulk veterinary drums
• Custom labels with dosing instructions for different species
• Multilingual cartons with country-specific branding

We help you comply with national and international packaging regulations while maintaining brand identity.

Regulatory Support and Documentation

BluepillExpress provides full documentation support to help you register and market Tetramisole HCl in your country.

Available Documents:

• WHO-GMP Certificate
• Certificate of Pharmaceutical Product (COPP)
• Free Sale Certificate
• Certificate of Origin
• Certificate of Analysis (COA)
• Dossier in CTD/ACTD format
• Product specifications and MSDS
• Artwork mockups for regulatory approval

We have successfully registered Tetramisole in markets across Africa, Asia, Middle East, and CIS regions.

Private Label and Third-Party Manufacturing Process

Our streamlined production model is designed to deliver customized, branded, and regulatory-compliant Tetramisole HCl with minimal turnaround time.

Our Process:

1. Requirement Sharing: Select formulation, dosage strength, and packaging
2. Quotation & Agreement: Confirm pricing, MOQs, and production timelines
3. Artwork & Branding: Provide your artwork or allow us to design
4. Sample Development: Receive lab batch for approval/testing
5. Production & Quality Checks: WHO-GMP compliant manufacturing begins
6. Packing & Dispatch: Custom labeling and international shipping
7. Regulatory Assistance: Get help with registrations and renewals

We support MOQs starting at 50,000 tablets or 500 liters, making it ideal for both established distributors and emerging brands.

Global Reach and Export Capabilities

BluepillExpress proudly serves clients in over 50 countries across:

• Africa: Nigeria, Ethiopia, Ghana, Kenya, Tanzania
• Asia: Myanmar, Nepal, Bangladesh, Cambodia
• Middle East: Iraq, Jordan, Yemen, UAE
• CIS Countries: Kazakhstan, Armenia, Uzbekistan
• Latin America & Caribbean: Haiti, Dominican Republic, Honduras

Our clientele includes:

• Government tender participants
• International NGOs and public health agencies
• Veterinary distributors and animal health companies
• Private-label pharmaceutical companies

Commitment to Sustainability and Ethics

BluepillExpress believes in sustainable manufacturing and ethical business practices:

• Zero-discharge wastewater systems
• Solar-powered energy systems and LED usage
• Recyclable packaging options
• No child labor and gender-inclusive hiring
• Participation in public deworming and veterinary outreach programs

We align our practices with global sustainability and public health goals.

Why Choose BluepillExpress for Tetramisole HCl Manufacturing?

• WHO-GMP certified and export-focused
• Human and veterinary dosage forms available
• Customizable packaging and private labeling
• Complete regulatory support with CTD/ACTD dossiers
• Competitive pricing and flexible order volumes
• Proven global market presence and logistics support
• Ethical, compliant, and scalable operations

Whether you’re targeting public health contracts, veterinary clinics, or OTC deworming brands, BluepillExpress is your trusted manufacturing partner.

Conclusion

Tetramisole Hydrochloride remains a vital medication in the control and treatment of parasitic worm infections. Its versatility, affordability, and efficacy make it a preferred choice in both human and veterinary medicine.

BluepillExpress offers complete third-party manufacturing services for Tetramisole HCl with global quality standards, scalable production, and personalized support. With our end-to-end solutions, you can confidently launch, register, or distribute Tetramisole products under your brand—anywhere in the world.