Povidone-Iodin

Povidone-Iodine is a broad-spectrum antiseptic and disinfectant used extensively in clinical, surgical, dental, and personal hygiene settings. Recognized for its ability to eliminate bacteria, fungi, viruses, protozoa, and spores, Povidone-Iodine has become a standard treatment and prevention agent in wound care, infection control, and preoperative preparation.

At BluepillExpress, we specialize in the third-party manufacturing of Povidone-Iodine formulations for a wide range of pharmaceutical, clinical, and consumer applications. With WHO-GMP certified facilities, a strong regulatory foundation, and export readiness, BluepillExpress serves global partners with customized production, superior quality assurance, and complete documentation support.

Product Overview

Product Name: Povidone-Iodine
Therapeutic Class: Topical Antiseptic / Disinfectant
Available Dosage Forms and Strengths:

• Topical Solution: 5%, 7.5%, 10% w/v
• Surgical Scrub: 4%, 7.5%, 10%
• Ointment: 5% or customized as per requirement
• Mouthwash / Gargle: 1%
• Suppositories (on request for gynecological applications)
• Wound Dressing / Swab Sticks / Medicated Pads (optional development)

Packaging Options:

• Bottles (50 mL to 5 L capacity) with tamper-evident caps
• Tubes for ointments (15 g to 100 g)
• Bulk containers for institutional supply
• Custom private label packaging for domestic and international markets

Pharmacological Action and Benefits

Povidone-Iodine is a stable chemical complex of polyvinylpyrrolidone (PVP) and elemental iodine. Upon application, it releases free iodine in a controlled manner, which penetrates microbial cell walls and oxidizes essential proteins, enzymes, and nucleotides, leading to irreversible microbial death.

Key Features and Benefits:

• Broad-spectrum antimicrobial action (bacteria, viruses, fungi, spores)
• Non-irritating, non-stinging, and non-staining formulation
• Effective even in the presence of blood, pus, or serum
• No risk of microbial resistance with repeated use
• Safe for long-term topical application under medical supervision

Mechanism of Action

The antimicrobial activity of Povidone-Iodine is due to the gradual release of free iodine upon contact with skin or mucous membranes. This iodine disrupts microbial metabolism by:

• Denaturing proteins and enzymes
• Disrupting cell membranes
• Oxidizing nucleic acids

This action leads to rapid cell lysis and death of pathogenic organisms, with minimal toxicity to human tissues when used correctly.

Indications

Povidone-Iodine is indicated for:

• Preoperative skin disinfection
• Surgical hand scrubs for healthcare professionals
• Treatment of minor wounds, cuts, abrasions, burns, and ulcers
• Prevention of infection in incisions and sutures
• Oral hygiene (gargles) for sore throat, oral ulcers, and dental surgeries
• Vaginal infections (in suppository or douche form)
• First-aid antiseptic for home and clinical use
• Hospital-grade sanitation and disinfection

The product is widely accepted across clinical, surgical, dental, veterinary, and consumer care domains.

Why Choose BluepillExpress for Povidone-Iodine Manufacturing?

1. WHO-GMP Certified Facilities with Specialized Infrastructure

BluepillExpress manufactures Povidone-Iodine in dedicated antiseptic production areas, designed to handle aqueous, semi-solid, and powder-based formulations. Our infrastructure includes:

• Stainless steel reactors and mixing vessels
• GMP-compliant filling and bottling lines
• Cleanrooms with HEPA filters and HVAC controls
• Fully automated ointment and solution lines
• Tube-filling and capping machinery with high accuracy

2. Formulation Customization and R&D Support

We offer custom development services to meet client needs:

• pH-balanced and alcohol-free formulations
• Non-foaming or foaming variants (for surgical scrub)
• Enhanced skin-soothing versions with allantoin or aloe vera
• Sugar-free or colorant-free oral gargles
• Combination products (e.g., Povidone-Iodine + Lidocaine)
• Controlled-release patches, wipes, or dressings (on demand)

Our R&D and formulation experts assist in product development, sample creation, and technology transfer.

Comprehensive Quality Assurance

All Povidone-Iodine formulations undergo extensive quality testing before batch release:

• Assay for iodine content and free iodine availability
• pH and viscosity measurement
• Microbial limit testing
• Stability under different temperature and light conditions
• Uniformity and content verification (ointment/tube forms)
• Compatibility testing with packaging material
• Preservative efficacy testing (for mouthwash/gargle formulations)

BluepillExpress follows USP, BP, IP, and EP standards depending on client requirements.

Regulatory Documentation and Global Compliance

We provide full regulatory documentation to support global product registrations:

• Certificate of Analysis (CoA)
• Batch Manufacturing Records (BMR)
• Certificate of Origin (CoO)
• Free Sale Certificate (FSC)
• Product Specifications and MoA
• MSDS (Material Safety Data Sheet)
• GMP and ISO 9001:2015 Certifications
• CTD/ACTD dossiers for regulated/semi-regulated markets

Our regulatory team supports clients through submission processes, query responses, and validation protocols across markets like Asia, Africa, CIS, and Latin America.

Private Label and Contract Packaging Services

BluepillExpress offers full private label manufacturing and packaging support for Povidone-Iodine products:

• Custom bottle shapes, colors, and caps
• Multilingual labels and inserts as per export market requirements
• Branding with client logo, layout, and corporate colors
• Carton packaging in single or bulk units
• Tamper-proof shrink sleeves, QR coding, and barcoding
• Eco-conscious packaging options using recyclable materials

We help clients accelerate market launch with ready-to-brand packaging solutions.

Export Expertise and Global Supply Chain

BluepillExpress serves clients across 35+ countries with seamless international supply chain management:

• Dedicated export division for logistics, documentation, and registration
• Pre-shipment inspection coordination (SGS, Intertek, Bureau Veritas)
• Temperature-controlled transport for sensitive solutions
• Support for government tender supply, NGO procurement, and institutional sales
• Flexible MOQ options for startups and large-scale buyers alike

Our experience with public health systems, hospital chains, and consumer brands positions us as a versatile partner for international collaborations.

Third-Party Manufacturing Workflow

Our structured process ensures quality, efficiency, and transparency throughout the third-party manufacturing journey:

1. Requirement Gathering
   • Product form, strength, packaging, destination market, regulatory scope
2. Commercial Agreement
   • Quotation, terms, NDA, artwork guidelines
3. Product Development (if needed)
   • Trial batch, packaging mock-ups, compatibility studies
4. Bulk Production
   • WHO-GMP batch manufacturing with in-process controls
5. Quality Assurance and Documentation
   • Final QC release, CoA generation, BMR review
6. Labeling, Packaging, and Shipping
   • Custom branding, dispatch, and export coordination

Lead Time: 30–40 working days (standard); shorter timelines available for repeat orders.

Client Profiles Served

Our Povidone-Iodine manufacturing solutions are ideal for:

• Pharmaceutical marketing companies
• Hospital supply chains and institutional procurement agencies
• Retail pharmacy and FMCG brands
• Government and NGO health programs
• Distributors and importers of antiseptic products

Whether for clinical, OTC, or personal care use, we provide scalable and compliant production for diverse client needs.

Advantages of Partnering with BluepillExpress

• WHO-GMP certified production with scalable output
• Customization across dosage forms, strengths, and packaging
• Full support for export compliance and global registration
• Competitive pricing with flexible batch sizes
• High-quality raw materials and validated formulations
• Transparent, secure, and confidential third-party partnerships
• Dedicated support team for formulation, design, and regulatory filing

Conclusion

Povidone-Iodine remains one of the most trusted antiseptic agents worldwide due to its broad-spectrum activity, versatility, and clinical efficacy. As demand rises in the wake of increased hygiene awareness and infection control, the need for reliable and scalable manufacturing partners becomes critical.

BluepillExpress brings together the best of manufacturing excellence, regulatory expertise, and customized client service to support your brand’s success. From hospitals and pharmacies to NGOs and global distributors, our third-party manufacturing solutions for Povidone-Iodine meet international quality benchmarks and help deliver life-saving products to those who need them.