Magnesium Hydroxide and Aluminium Hydroxide

Magnesium Hydroxide and Aluminium Hydroxide are antacids widely used for the treatment of gastric acidity, indigestion, peptic ulcers, and gastroesophageal reflux disease (GERD). These compounds are highly effective in neutralizing excess stomach acid, reducing symptoms such as heartburn, bloating, and upset stomach.

At BluepillExpress, we offer comprehensive third-party manufacturing services for a wide range of Magnesium Hydroxide and Aluminium Hydroxide formulations, including oral suspensions and chewable tablets, customized to the needs of our domestic and international clients. With our WHO-GMP certified facilities, ISO 9001:2015 accreditation, and strong commitment to regulatory compliance and patient safety, we deliver scalable, efficient, and quality-assured solutions to global pharmaceutical brands.

Product Overview: Magnesium Hydroxide & Aluminium Hydroxide

Magnesium Hydroxide (Mg(OH)₂) and Aluminium Hydroxide (Al(OH)₃) work as non-systemic antacids. When consumed, they react with gastric acid (HCl) to form water and neutral salts, thereby raising stomach pH and relieving acid-related discomfort.

Mechanism of Action:

• Magnesium Hydroxide: Rapid-acting, offers fast acid neutralization and mild laxative effect
• Aluminium Hydroxide: Slower in onset, provides prolonged acid suppression and mild constipating effect
• Combination Benefit: Balances the gastrointestinal motility (neutral laxative effect)

These agents are often combined with Simethicone, Oxetacaine, or digestive enzymes to enhance therapeutic benefit, reduce gas formation, and offer better tolerability.

Therapeutic Applications

Formulations containing Magnesium Hydroxide and Aluminium Hydroxide are used in the management of a wide range of gastrointestinal disorders, including:

• Hyperacidity and acid reflux
• Indigestion and dyspepsia
• Peptic ulcer disease
• GERD (Gastroesophageal Reflux Disease)
• Flatulence and abdominal bloating (in combination with Simethicone)
• Painful or burning stomach sensation
• Functional dyspepsia

These formulations are considered safe for short-term symptom relief and are widely prescribed in both prescription and OTC markets.

Why Choose BluepillExpress for Manufacturing?

BluepillExpress has extensive experience in manufacturing oral liquid and solid antacid formulations, offering complete end-to-end services from development to distribution.

Key Advantages:

• WHO-GMP & ISO 9001 certified facility
• Stringent in-house quality control and assurance
• Custom strengths and flavor profiles
• Specialized expertise in suspensions and chewable tablets
• Private and white label support for branding
• Regulatory documentation for global registrations
• Flexible MOQ and scalable capacity

Whether you are a new pharmaceutical startup, hospital supplier, tender participant, or international distributor, we provide a smooth, regulatory-compliant path from manufacturing to market.

Available Formulations

1. Magnesium Hydroxide + Aluminium Hydroxide Oral Suspension

• Standard Strength:
  • Magnesium Hydroxide 400 mg
  • Aluminium Hydroxide 400 mg
  • Simethicone 20 mg (optional)
• Flavor: Mint, orange, lemon (customizable)
• Packaging: 170 ml, 200 ml, 225 ml bottles
• Shelf Life: 24 months
• Dosage: As directed by physician, typically 5–10 ml after meals

This formulation is ideal for quick symptomatic relief, especially suitable for the OTC market.

2. Magnesium Hydroxide + Aluminium Hydroxide Chewable Tablets

• Tablet Strength: 250 mg + 250 mg (customizable)
• Packaging: Strip packs, blister packs (10×10, 20×10)
• Flavors: Peppermint, orange, strawberry
• Target Market: Pediatric and adult dyspepsia treatment

3. Fixed-Dose Combinations (FDCs)

On demand, we manufacture customized combinations with:

• Simethicone (anti-flatulent)
• Oxetacaine (local anesthetic for acid pain)
• Digestive enzymes (for better digestion)
• Domperidone (prokinetic agent, on prescription basis)
• Sugar-free and alcohol-free variants available

All formulations are manufactured to meet IP/BP/USP/EP specifications.

Manufacturing Capabilities

Our facilities are engineered to handle large-volume production while maintaining the integrity and stability of sensitive ingredients like magnesium and aluminium salts.

Infrastructure Features:

• High-shear mixers for uniform suspensions
• Liquid filling lines with nitrogen blanketing (to prevent oxidation)
• Automated syrup filling and capping machines
• Tablet compression machines with customized tooling
• Flavoring and color mixing tanks
• SS316L contact parts and sanitary piping
• Dust and contamination control systems
• Separate storage for acid-sensitive ingredients

All processes are governed by validated SOPs, ensuring consistency in each production cycle.

Quality Control and Quality Assurance

At BluepillExpress, product quality and patient safety are paramount. We follow stringent QC and QA protocols for every product batch.

Quality Parameters Tested:

• Identity and assay of Magnesium and Aluminium Hydroxide
• pH and viscosity (for suspensions)
• Uniformity of content and weight (for tablets)
• Microbial limit testing
• Specific gravity and appearance
• Palatability and flavor stability
• Sedimentation rate and resuspendability (suspensions)
• Dissolution and disintegration profiles (tablets)
• Stability studies under ICH guidelines

All products are released with a Certificate of Analysis (COA) and backed by Batch Manufacturing Records (BMRs) and Stability Data Reports.

Regulatory Support and Documentation

We provide complete regulatory documentation to support product registration in international markets.

Our Regulatory Documents Include:

• CTD/ACTD dossier (Module 1–5)
• WHO-GMP Certificate
• Free Sale Certificate (FSC)
• Certificate of Pharmaceutical Product (CoPP)
• Certificate of Origin (COO)
• Product composition and MSDS
• Method of analysis (MOA)
• Stability data and specifications
• Packaging and labeling proofs

We have successfully registered products in Africa, Asia, CIS, Latin America, and the Middle East, assisting clients with both public and private market entry.

Packaging and Customization

We offer a range of custom packaging solutions suited for retail and institutional use:

Oral Suspensions:

• HDPE/PET bottles (100 ml to 500 ml)
• Child-resistant and tamper-proof caps
• Printed cartons with multilingual inserts
• Shrink-wrapped packs for retail safety

Chewable Tablets:

• Blister packs with perforation options
• Aluminum foil packaging for enhanced shelf life
• Custom artwork and brand design
• QR code/serialization compliant with global traceability standards

Our in-house design team can create packaging that meets local language laws, branding preferences, and export regulations.

Private Label and White Label Manufacturing

For clients looking to launch their own branded product, BluepillExpress offers turnkey private label and white label services, including:

• Custom formulation development
• Brand name selection and design
• Regulatory documentation under your brand
• Flexible MOQs for trial or test markets
• Full confidentiality and trademark protection
• Sample development and marketing mockups
• Multilingual label printing and artwork

Our private label clients benefit from a quick go-to-market strategy, leveraging our manufacturing excellence and regulatory guidance.

Export Services and Global Reach

BluepillExpress is a trusted exporter to over 35 countries across Africa, Southeast Asia, Middle East, CIS, and Latin America.

Export Services Include:

• EXW, FOB, CIF, and DDP shipping terms
• Air and sea freight coordination
• Export clearance and documentation
• Temperature-sensitive logistics
• Country-specific labeling and packaging
• Coordination with NGOs, health departments, and tender authorities

We serve government tenders, humanitarian missions, NGOs, hospital networks, and international pharmacy chains.

Minimum Order Quantities (MOQs)

We offer flexible MOQs tailored to different client profiles:

• Low MOQ for startups or trial batches
• Medium MOQ for regional distributors and private label brands
• Bulk MOQ for government tenders or public health campaigns

Our account management team will provide customized MOQ details based on formulation, packaging type, and destination country.

Client Testimonials

“BluepillExpress’s suspension formulation met our exact standards for palatability and stability. It’s now the top-selling antacid in our chain.”
— Pharmacy Retailer, West Africa

“The chewable tablets we sourced from BluepillExpress had outstanding quality. Their private label service helped us launch quickly and professionally.”
— Pharmaceutical Brand Owner, Middle East

“For government tenders, they provided not just product but full regulatory support and logistics. Reliable and efficient.”
— Tender Consultant, Southeast Asia

Conclusion

Magnesium Hydroxide and Aluminium Hydroxide continue to play a key role in gastrointestinal healthcare, offering safe, effective relief for acid-related discomfort. As consumer demand for trusted, over-the-counter antacids grows globally, there is a substantial opportunity for pharmaceutical companies to capture market share with reliable, high-quality formulations.

At BluepillExpress, we offer everything you need—from research and formulation to regulatory documentation, production, packaging, and global export. Our manufacturing excellence, customer-centric approach, and compliance-driven systems ensure your product meets both market expectations and regulatory requirements.