Naproxen

BluepillExpress is a globally trusted name in the pharmaceutical industry, renowned for its unwavering commitment to quality, innovation, and regulatory compliance. As a certified third-party manufacturer based in India, BluepillExpress offers a comprehensive range of pharmaceutical manufacturing services for clients worldwide. Our specialization in pain management drugs, including nonsteroidal anti-inflammatory drugs (NSAIDs) like Naproxen, makes us the ideal partner for businesses seeking top-tier manufacturing capabilities without compromising on compliance or quality.

With extensive experience in regulatory frameworks, certifications, and a strong logistics network across over 140 countries, BluepillExpress ensures that your products reach global markets efficiently and safely.

Product Overview: Naproxen

Naproxen is a widely used nonsteroidal anti-inflammatory drug (NSAID) indicated for the treatment of pain, inflammation, and fever. It is commonly prescribed for conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, tendinitis, bursitis, menstrual cramps, and general musculoskeletal pain. Available in both over-the-counter (OTC) and prescription forms, Naproxen is a key product in the global pain relief market.

At BluepillExpress, we manufacture Naproxen in multiple forms, including:

• Naproxen Tablets (250 mg, 375 mg, 500 mg)
• Naproxen Sodium Tablets
• Naproxen Extended-Release Tablets
• Naproxen Combination Formulations (e.g., with Esomeprazole or Domperidone)
• Customized packaging and dosage forms upon client request

Why Choose BluepillExpress for Naproxen Manufacturing

1. GMP & WHO-Certified Facilities

Our state-of-the-art manufacturing units are fully compliant with WHO-GMP, ISO, and other international quality certifications, ensuring that every batch of Naproxen we produce meets global standards. With stringent protocols in place, we deliver products that are safe, effective, and consistent.

2. High-Quality Raw Material Sourcing

BluepillExpress sources active pharmaceutical ingredients (APIs) for Naproxen from pre-approved, reputable vendors. All raw materials undergo rigorous testing to meet pharmacopeial standards (USP/BP/EP/JP/IP), ensuring superior efficacy and safety.

3. Custom Formulations & Private Labeling

We work with pharmaceutical brands, distributors, and healthcare providers to offer custom formulations of Naproxen tailored to specific market needs. Our private labeling services allow businesses to market Naproxen under their own brand name while leveraging BluepillExpress’s manufacturing excellence.

4. Flexible Batch Sizes

Whether you require small batches for clinical trials or large-scale production for commercial distribution, we offer flexible production volumes to suit your business model and demand forecasts.

5. Regulatory Documentation Support

We provide end-to-end support for regulatory documentation, including Certificate of Analysis (COA), Batch Manufacturing Record (BMR), Certificate of Pharmaceutical Product (CoPP), MSDS, and Dossier Preparation in CTD/eCTD formats for international registration.

Manufacturing Process of Naproxen at BluepillExpress

1. Formulation Development

Our R&D team begins with an in-depth understanding of the client’s formulation goals. We develop stable and bioavailable formulations of Naproxen using advanced technology and compatibility studies.

2. Granulation and Blending

The API and excipients are subjected to wet or dry granulation processes to achieve uniformity and flow properties. Our advanced blenders ensure homogeneous mixing, reducing batch-to-batch variation.

3. Compression or Encapsulation

Using automated tablet compression machines or encapsulators, Naproxen is processed into its final solid dosage form. Our machinery ensures optimal hardness, friability, and dissolution profiles.

4. Coating and Polishing

Film-coating is applied to enhance the stability, taste-masking, and controlled-release properties of Naproxen tablets. Coated tablets are then polished for a premium finish.

5. Quality Control and Testing

Each batch is subjected to in-process and post-process quality control tests, including:

• Assay and potency
• Dissolution and disintegration
• Uniformity of weight
• Stability testing
• Microbial testing
• Heavy metal analysis

Only batches that meet all specifications proceed to packaging.

Packaging Capabilities

BluepillExpress provides versatile packaging options to meet global standards and local preferences. Packaging services include:

• Blister Packs (Alu-Alu, PVC, PVDC)
• HDPE and PET Bottles
• Strip Packs
• Custom Branding & Labeling
• Multilingual packaging materials as per export requirements

We also offer tamper-evident and child-resistant packaging solutions to ensure patient safety and product integrity.

Quality Assurance and Compliance

Quality is the cornerstone of our operations. Our dedicated QA/QC teams implement a zero-defect policy backed by:

• Adherence to ICH Guidelines for stability and shelf-life
• Compliance with GMP, ISO 9001:2015, and HACCP
• Regular internal audits and mock inspections
• Batch traceability and serialization support

We maintain full transparency throughout the manufacturing lifecycle and ensure that all Naproxen formulations are fully traceable and auditable.

International Market Reach

BluepillExpress serves clients across Africa, South-East Asia, the Middle East, CIS countries, Europe, and Latin America. We understand the regulatory nuances of each market and tailor our manufacturing and documentation to meet country-specific requirements, including:

• ANVISA (Brazil)
• MHRA (UK)
• TGA (Australia)
• US FDA (for export-ready dossiers)
• PPB (Kenya)
• NDA (Uganda)

We support export through compliant documentation, logistics coordination, and customs clearance assistance.

Benefits of Partnering with BluepillExpress

• Cost-Effective Manufacturing without compromising on quality
• Access to advanced pharmaceutical technologies
• Comprehensive support from product development to commercialization
• End-to-end supply chain visibility
• On-time delivery with competitive turnaround times
• Complete confidentiality and IP protection

Therapeutic Importance of Naproxen

Naproxen has become a cornerstone in pain management due to its longer half-life, allowing for less frequent dosing compared to other NSAIDs. This enhances patient adherence and comfort, making it a preferred choice among prescribers for:

• Chronic inflammatory conditions (e.g., arthritis)
• Acute pain (e.g., dental pain, post-operative pain)
• Migraine and headache management
• Dysmenorrhea (painful menstruation)
• Sports injuries and soft tissue inflammation

Our Naproxen formulations are designed for rapid onset of action, prolonged relief, and minimal gastrointestinal side effects, especially when combined with gastroprotective agents.

Sustainability and Ethical Manufacturing

At BluepillExpress, we believe in responsible manufacturing practices. Our commitment to sustainability includes:

• Eco-friendly waste management systems
• Reduced water and energy consumption
• Use of green chemistry principles
• Ethical labor practices and a safe working environment
• Corporate social responsibility (CSR) initiatives supporting healthcare access

We are continually evolving our processes to align with global environmental standards while maintaining production efficiency.

Client Engagement & Support

We provide dedicated account managers for every client to ensure seamless coordination and personalized service. From first inquiry to final delivery, our team is available 24/7 to address your concerns, share updates, and ensure smooth operations.

We also offer after-sales technical support, including training materials, pharmacovigilance data sharing, and product customization based on client feedback.

Conclusion

BluepillExpress stands as a trusted leader in third-party manufacturing for Naproxen and related NSAID formulations. With our deep industry expertise, advanced infrastructure, and client-centric approach, we empower pharmaceutical businesses to scale effectively and expand into new markets with confidence.

By choosing BluepillExpress as your Naproxen manufacturing partner, you gain access to world-class production standards, a robust regulatory support system, and a team committed to your brand’s long-term success.

Let us be the driving force behind your brand’s growth—where science, service, and quality converge.