Description
TRIPHAGE PG2 TABLET is an advanced fixed-dose combination therapy containing Pioglitazone and Glimepiride, designed to offer optimal glycemic control in patients with Type 2 Diabetes Mellitus. It is indicated for use when monotherapy is inadequate in maintaining blood glucose levels.
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Glimepiride is a sulfonylurea that stimulates insulin release from pancreatic beta cells, helping reduce postprandial and fasting blood glucose.
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Pioglitazone is a thiazolidinedione that improves insulin sensitivity in peripheral tissues and reduces hepatic glucose output.
Together, these agents provide a synergistic effect, enhancing insulin action and improving glucose uptake across multiple organs.
Oral Antidiabetic Combination
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Glimepiride: Stimulates insulin secretion by acting on ATP-sensitive potassium channels in beta cells of the pancreas.
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Pioglitazone: Activates PPAR-γ receptors, improving insulin sensitivity and glucose uptake in adipose tissue and muscle, while decreasing hepatic glucose production.
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Type 2 Diabetes Mellitus (when monotherapy is inadequate)
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Patients requiring dual oral antidiabetic therapy
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Suitable for improving HbA1c levels in insulin-resistant patients
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Dual-action approach for better glycemic control
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Reduces both fasting and post-meal blood sugar levels
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Enhances insulin sensitivity and pancreatic insulin release
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Convenient once-daily dosing
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Helps delay the need for insulin therapy in diabetic patients
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Typically administered once daily, preferably with breakfast
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Dosage to be individualized based on patient response and physician’s recommendation
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Blood glucose monitoring is essential to determine efficacy and safety
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Monitor liver function regularly due to Pioglitazone component
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Use with caution in patients with heart failure
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Risk of hypoglycemia, especially in elderly or those with renal impairment
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Not recommended for Type 1 diabetes or diabetic ketoacidosis
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Periodic monitoring of HbA1c and blood glucose is advised
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Hypoglycemia
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Weight gain
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Edema
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Headache
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Muscle pain
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Upper respiratory tract infections
At BLUEPILL EXPRESS, we pride ourselves on delivering pharmaceutical excellence through internationally certified facilities. TRIPHAGE PG2 TABLET is manufactured under WHO-GMP and ISO standards, ensuring safety, efficacy, and global compliance.
We are a global exporter of all types of medicines, supplying high-quality pharmaceutical products to markets across Asia, Africa, Latin America, CIS, and the Middle East. Our commitment to regulatory support, private labeling, and custom packaging makes us a preferred partner in third-party manufacturing.
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