Description

TRAZOSIG 100 TABLET is a prescription medication formulated with Trazodone Hydrochloride 100 mg, a serotonin antagonist and reuptake inhibitor (SARI) used in the management of major depressive disorder (MDD), generalized anxiety, and chronic insomnia. Trazodone is widely prescribed for its dual action of improving mood while promoting restful sleep, making it especially useful in cases where depression coexists with sleep disturbances.

TRAZOSIG 100 works by modulating serotonin levels in the brain, primarily blocking serotonin type 2 (5-HT2) receptors and inhibiting serotonin reuptake. This combined mechanism helps restore emotional balance while minimizing overstimulation, offering therapeutic benefit for both mood disorders and sleep problems.

Antidepressant / Anxiolytic / Hypnotic

Trazodone selectively inhibits serotonin reuptake and blocks 5-HT2 receptors, enhancing serotonin activity in the central nervous system. This dual mechanism improves mood and sleep architecture without causing the stimulating effects commonly seen with other antidepressants.

• Major Depressive Disorder (MDD)

• Anxiety Disorders

• Insomnia (particularly depression-related)

• Post-Traumatic Stress Disorder (off-label)

• Chronic pain syndromes (off-label)

• Treats depression and associated sleep disorders

• Less sexual dysfunction compared to SSRIs

• Lower risk of dependency vs. benzodiazepines

• Non-habit forming sedative effect

• May help with fibromyalgia-related sleep issues

• Adults (Depression): 150 mg/day in divided doses (initial), titrated up to 300–400 mg/day

• For insomnia: Often administered as 50–100 mg at bedtime

• Should be taken with food to improve absorption

• Dose adjustments based on clinical response and tolerability

• Use cautiously in patients with cardiac disease or arrhythmia

• May cause drowsiness—avoid driving or operating machinery

• Risk of serotonin syndrome if combined with serotonergic agents

• Avoid alcohol and CNS depressants

• Not recommended during pregnancy unless absolutely necessary

• Drowsiness or sedation

• Dry mouth

• Dizziness or orthostatic hypotension

• Blurred vision

• Nausea

• Rare: priapism (prolonged erection), QT prolongation

BLUEPILL EXPRESS is a globally trusted third-party manufacturer and exporter of high-quality generic pharmaceuticals. TRAZOSIG 100 TABLET is produced under stringent WHO-GMP and ISO-certified conditions, ensuring efficacy, safety, and compliance with international regulatory standards.

• High-grade active pharmaceutical ingredients (APIs)

• Private labeling and custom branding available

• Reliable documentation: COA, MSDS, stability data, export paperwork

• Export coverage across Africa, Asia, Latin America, CIS, and Europe

• Flexible MOQ and logistics support for global partners