Description
SITAJAN MET 50/1000 TABLET is a fixed-dose oral antidiabetic combination medication that integrates the therapeutic benefits of:
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Sitagliptin Phosphate 50 mg – a DPP-4 inhibitor
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Metformin Hydrochloride 1000 mg – a biguanide class agent
This dual therapy is indicated for adults with Type 2 Diabetes Mellitus who are unable to achieve adequate glycemic control with monotherapy. It is especially beneficial for those requiring a higher dose of Metformin to maintain blood sugar levels.
Sitagliptin increases incretin levels, which in turn stimulates insulin release and reduces glucagon secretion in a glucose-dependent manner. Metformin decreases hepatic glucose production, enhances insulin sensitivity, and improves peripheral glucose uptake.
Together, they provide a synergistic effect, resulting in improved fasting plasma glucose, postprandial glucose, and HbA1c levels—without significant weight gain or increased risk of hypoglycemia.
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Type 2 Diabetes Mellitus in adults
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Second-line or combination therapy with lifestyle modification
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Patients inadequately controlled on Metformin monotherapy
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Dual-action therapy for enhanced blood sugar regulation
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High-dose Metformin (1000 mg) supports stronger glucose control
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Reduces both fasting and post-meal blood glucose levels
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Low risk of hypoglycemia and weight neutrality
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Supports cardiovascular and metabolic health when used long-term
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Sitagliptin – Dipeptidyl Peptidase-4 (DPP-4) Inhibitor
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Metformin – Biguanide oral hypoglycemic
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To be taken orally, usually twice daily with meals
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Dosage adjustments should be made under medical supervision
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Not recommended for patients with significant renal impairment
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Regular monitoring of blood glucose and renal function is advised
Manufactured in WHO-GMP and ISO-certified facilities, SITAJAN MET 50/1000 TABLET meets stringent international quality standards. Each batch is subjected to rigorous testing to ensure purity, potency, and patient safety.
BLUEPILL EXPRESS is a leading global exporter and third-party manufacturer of quality pharmaceutical products. Our robust supply chain and compliance-driven production standards make us a trusted partner for importers, wholesalers, hospitals, and government tenders across:
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Asia
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Africa
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Middle East
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CIS Countries
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Latin America
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Europe
We offer customizable packaging, regulatory documents (COA, MSDS, Stability Data), and end-to-end export solutions.
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