IndiaMart
FIEO
At Bluepillexpress, we take pride in being a trusted third-party pharmaceutical manufacturer committed to delivering high-quality, safe, and effective medicines to partners worldwide. One of our flagship offerings is Silver Sulphadiazine Cream, a widely used topical antimicrobial agent prescribed for the prevention and treatment of infections in burn wounds and other skin injuries. Our manufacturing processes adhere to the highest standards of Good Manufacturing Practices (GMP) and international quality regulations, making us the ideal partner for companies looking to expand their product portfolios with reliable and proven treatments.
About Silver Sulphadiazine
Silver Sulphadiazine is an antimicrobial cream used primarily for the prevention and treatment of wound infections in patients with second- and third-degree burns. It combines silver’s broad-spectrum antibacterial properties with sulphadiazine, a sulfonamide antibiotic, to inhibit bacterial growth and promote wound healing. Silver ions disrupt bacterial cell walls and DNA, while sulphadiazine interferes with folic acid synthesis in bacteria, ensuring effective control of a wide range of Gram-positive and Gram-negative pathogens.
Therapeutic Applications
- Burn Care: Silver Sulphadiazine is the standard of care for preventing and treating infections in thermal burns.
- Skin Ulcers: Used in pressure sores and leg ulcers to minimize infection risks.
- Minor Cuts & Abrasions: In select cases, prescribed to reduce infection risk in contaminated wounds.
- Skin Grafts & Donor Sites: Applied to prevent infections and support graft take.
- Surgical Wounds: In certain situations, applied under medical supervision to protect high-risk surgical sites.
Why Choose Bluepillexpress for Silver Sulphadiazine Manufacturing?
1. State-of-the-Art Facilities
Our manufacturing units are equipped with advanced machinery and cleanroom environments designed specifically for sterile and semi-solid formulations like creams and ointments. We ensure uniform particle size distribution of silver sulphadiazine for consistent potency and optimal therapeutic action.
2. Stringent Quality Assurance
Every batch undergoes rigorous quality checks, including:
- Assay for silver and sulphadiazine content
- pH testing
- Microbial limits
- Uniformity of weight and consistency
- Stability studies to validate shelf-life
Our Quality Assurance (QA) and Quality Control (QC) teams meticulously monitor all stages of production, from raw material sourcing to packaging.
3. Certified Processes
Bluepillexpress holds certifications like WHO-GMP, ISO 9001:2015, and local drug regulatory approvals, ensuring our partners can confidently market our products globally.
4. Customizable Packaging & Branding
We offer complete private and white-label manufacturing solutions. Whether you want tubes in 10g, 20g, 30g, or bulk containers for hospital use, we can customize packaging and labeling to meet your market’s regulatory and branding needs.
5. Comprehensive Documentation
We provide:
- Certificates of Analysis (CoA)
- Certificates of Good Manufacturing Practices (CGMP)
- Batch Manufacturing Records (BMR)
- Product dossiers for registration in international markets
6. Flexible Production Capacity
From small batches for niche markets to large-scale commercial production, we accommodate all volume requirements while maintaining consistent quality.
7. Expert Regulatory Support
Our experienced regulatory affairs team assists you with product registrations, regulatory submissions, and documentation, ensuring your Silver Sulphadiazine product complies with your country’s health authority standards.
Our Manufacturing Process for Silver Sulphadiazine
Step 1: Raw Material Procurement & Testing
We source pharmaceutical-grade silver nitrate and sulphadiazine from audited and approved suppliers. Raw materials are tested for identity, purity, and compliance with pharmacopeial standards.
Step 2: Synthesis of Silver Sulphadiazine
Under controlled conditions, silver nitrate is reacted with sulphadiazine in an aqueous medium to produce a fine, white, crystalline powder of silver sulphadiazine. This step is performed in GMP-compliant reactors to ensure high purity and uniformity.
Step 3: Cream Base Preparation
A stable oil-in-water emulsion is prepared using pharmaceutically approved excipients, including emulsifying agents, humectants, and preservatives, to form a smooth, non-irritating base.
Step 4: Incorporation of Silver Sulphadiazine
The active ingredient is dispersed into the cream base under sterile, homogenized conditions to ensure even distribution of the silver sulphadiazine particles.
Step 5: Filling & Packaging
The finished cream is filled into sterilized tubes or containers using automated filling lines in Class 100,000 cleanrooms. Tubes are crimped, labeled, and packed into cartons, followed by batch coding and serialization if required.
Step 6: Quality Control Testing
Finished products undergo comprehensive in-process and final release testing before distribution. Only batches that meet our stringent quality specifications are released for sale.
Stability & Shelf-Life
Our standard Silver Sulphadiazine formulation offers a shelf-life of 24 months when stored below 25°C in its original, unopened packaging, protecting it from light and moisture.
Safety & Precautions
Our product labeling includes clear instructions on usage, warnings, contraindications, and potential side effects, helping healthcare professionals and patients use the cream safely. Common precautions we highlight include:
- Avoiding use in patients with known sulfonamide allergies.
- Monitoring for signs of leukopenia or systemic absorption, especially with extensive burns.
- Advising pregnant and breastfeeding women to consult their doctor before use.
Global Supply & Logistics
Bluepillexpress has a proven track record of exporting medicines to Asia, Africa, Europe, and Latin America. Our logistics team ensures:
- Timely delivery with temperature-controlled shipping where needed.
- Complete export documentation, including Certificate of Origin and Bill of Lading.
- Assistance with customs clearance and import formalities.
Commitment to Sustainability
We recognize the importance of environmentally responsible manufacturing. Our facilities operate with optimized energy consumption, wastewater treatment plants, and eco-friendly packaging options, supporting a greener pharmaceutical supply chain.
Partner with Bluepillexpress Today
Whether you’re a distributor, hospital chain, government procurement agency, or brand owner, Bluepillexpress is your ideal third-party manufacturer for Silver Sulphadiazine Cream. Partner with us for unmatched quality, competitive pricing, regulatory support, and timely supply.
Contact our business development team today to discuss your requirements, request a sample, or obtain a quotation for your next order.
