Secnidazole

Secnidazole is a potent antiprotozoal and antibacterial agent belonging to the nitroimidazole class of medications. It is widely used in the treatment of intestinal amoebiasis, giardiasis, trichomoniasis, and bacterial vaginosis, thanks to its broad-spectrum activity against anaerobic microorganisms. What sets Secnidazole apart from other nitroimidazoles like Metronidazole is its prolonged half-life, which allows for single-dose therapy—a key advantage for improving patient compliance and therapeutic outcomes.

As an essential drug in regions where protozoal infections and anaerobic bacterial infections are prevalent, Secnidazole is in high demand across public health programs, hospital formularies, and retail pharmaceutical markets.

At BluepillExpress, we offer end-to-end third-party manufacturing services for Secnidazole, supporting pharmaceutical companies, NGOs, and health agencies with scalable, high-quality, and regulatory-compliant solutions under their own brand.

About BluepillExpress

BluepillExpress is a WHO-GMP certified pharmaceutical manufacturing company based in India, with a global footprint across Africa, Southeast Asia, CIS countries, the Middle East, and Latin America. We specialize in third-party and contract manufacturing of generic, branded, and institutional medicines with a focus on quality, affordability, and regulatory compliance.

Our services include:

• WHO-GMP & ISO-certified manufacturing facilities
• Private label and white label production
• Full regulatory support (COPP, COA, CTD/ACTD dossiers)
• Flexible MOQ options and competitive pricing
• Global logistics, export documentation, and shipping

With years of experience in manufacturing anti-infective, antiprotozoal, and gastrointestinal drugs, BluepillExpress is the preferred partner for companies looking to manufacture and market Secnidazole worldwide.

Pharmacological Overview

• Generic Name: Secnidazole
• Pharmacological Class: Nitroimidazole derivative
• Therapeutic Class: Antiprotozoal / Antibacterial
• Mechanism of Action: Disrupts DNA synthesis in anaerobic organisms
• Route of Administration: Oral
• Dosage Forms: Tablets, Granules for Suspension (on request)

Mechanism of Action

Secnidazole, like other nitroimidazoles, undergoes enzymatic reduction within the anaerobic microorganism, resulting in the production of free radicals. These free radicals bind to microbial DNA and inhibit nucleic acid synthesis, ultimately causing cell death.

What makes Secnidazole distinct is its long half-life of 17–29 hours, which allows for once-daily or single-dose therapy in conditions typically requiring multiple doses of Metronidazole or Tinidazole. This improved pharmacokinetic profile results in:

• Higher compliance rates
• Sustained therapeutic levels
• Enhanced microbial clearance

Therapeutic Indications

Secnidazole is clinically indicated for the treatment of:

• Amoebiasis (Intestinal and Hepatic forms)
• Giardiasis
• Trichomoniasis
• Bacterial Vaginosis
• Anaerobic Bacterial Infections (off-label in some settings)

Due to its broad antimicrobial activity and ease of administration, it is commonly prescribed as a single-dose therapy, making it especially useful in mass-treatment campaigns and resource-limited settings.

Dosage Forms and Strengths Manufactured by BluepillExpress

At BluepillExpress, we manufacture Secnidazole in compliance with IP, BP, and USP standards, ensuring consistency, efficacy, and stability.

1. Secnidazole Tablets

• Strengths: 500 mg, 1000 mg, 2000 mg
• Form: Uncoated or film-coated tablets
• Packaging: Blister strips (1×1, 1×2, 1×4), cartons, or bulk packs
• Shelf Life: 36 months
• Standards: IP/BP/USP (based on market requirement)

2. Secnidazole Granules for Suspension (on request)

• Strength: Equivalent to 1 g or 2 g per sachet
• Form: Flavored dry granules to be reconstituted in water
• Packaging: Sachets with individual foil packs
• Use Case: Pediatric and adult administration

Customized formulations and fixed-dose combinations can also be developed based on regulatory approval and market needs.

Manufacturing Infrastructure

BluepillExpress operates from a WHO-GMP, ISO 9001:2015, and Schedule M-certified facility, designed to manufacture high-volume, quality-assured pharmaceutical formulations.

Facility Features:

• Fully automated tablet compression lines
• Advanced coating equipment (film and enteric)
• Dedicated lines for dry syrup and granule sachets
• Dehumidified clean rooms with HVAC
• On-site analytical laboratories with HPLC, UV, dissolution, and microbiology setups
• Packaging lines for blister, strip, and sachet forms

Our infrastructure allows us to scale production efficiently—from pilot batches to bulk commercial orders—without compromising quality or timelines.

Quality Control and Quality Assurance

We implement a stringent Quality Management System (QMS) at every stage of manufacturing. All Secnidazole batches undergo detailed testing in our in-house laboratories and are released only after passing all quality parameters.

QC Testing Includes:

• API identity and assay
• Tablet weight uniformity and hardness
• Dissolution and disintegration time
• Microbial limit testing
• Stability studies (accelerated and real-time)
• Granule reconstitution and palatability testing (for suspensions)

Documents Provided:

• Certificate of Analysis (COA)
• Batch Manufacturing Record (BMR)
• Raw Material Specifications
• Finished Product Specifications
• Stability Data Reports

All testing complies with the latest IP, BP, or USP monographs and meets the requirements of international regulatory bodies.

Packaging and Labeling Solutions

BluepillExpress offers customizable, export-grade packaging solutions designed for retail, institutional, and government supply channels.

Tablet Packaging Options:

• PVC/Alu blister strips
• Alu-Alu blister packs
• HDPE bottles with desiccant
• Unit-dose foil packs for single-dose therapy
• Multilingual cartons and leaflets (as per local regulations)

Suspension Granule Packaging (on request):

• Triple-layer laminated sachets
• Individual unit boxes or bundled sets
• Reconstitution instructions included
• Barcoded and serialized packaging available

All labeling and branding elements can be tailored to match your private label or institutional requirements.

Regulatory Support and Documentation

BluepillExpress provides complete regulatory and export documentation to facilitate smooth registration and market entry in your target country.

Documents Offered:

• WHO-GMP Certificate
• Certificate of Pharmaceutical Product (COPP)
• Certificate of Analysis (COA)
• Free Sale Certificate
• Certificate of Origin
• Product Specification Sheet and MSDS
• CTD/ACTD Dossier (for registration)
• Stability Data
• Mockups and final artwork

We have successfully registered products in markets governed by:

• NAFDAC (Nigeria)
• PPB (Kenya)
• FMHACA (Ethiopia)
• SFDA (Saudi Arabia)
• DRAP (Pakistan)
• MOH authorities across Asia, Africa, and CIS nations

Private Label and Contract Manufacturing Process

BluepillExpress simplifies the contract manufacturing journey through a transparent, step-by-step partnership.

How It Works:

1. Product Inquiry: Share strength, dosage form, and packaging requirements
2. Quotation & Terms: Receive pricing, MOQs, and production timelines
3. Artwork Finalization: Custom design services or use your existing layout
4. Sample Batch: Lab samples or exhibit batches for approval/registration
5. Commercial Manufacturing: Full-scale production under strict QA
6. Labeling & Packing: Done under your brand name
7. Shipping & Documentation: Global logistics and compliance paperwork

We support low MOQs for emerging brands and bulk tenders for large procurement agencies.

Export Markets and Clientele

BluepillExpress exports Secnidazole formulations to over 50 countries and supports clients in:

• Africa: Nigeria, Ghana, Kenya, Ethiopia, Angola
• Asia: Myanmar, Nepal, Bangladesh, Cambodia
• Middle East: Iraq, Jordan, UAE, Yemen
• CIS Countries: Kazakhstan, Uzbekistan, Kyrgyzstan
• Latin America & Caribbean: Haiti, Dominican Republic, Bolivia

Our clients include:

• Private-label pharmaceutical companies
• Government health ministries and procurement agencies
• NGOs and humanitarian organizations
• Hospital and institutional buyers

Sustainability and Social Responsibility

We take pride in our sustainable, ethical, and socially responsible business model, which includes:

• Eco-friendly water and waste management systems
• Energy-efficient manufacturing practices
• Recyclable packaging solutions
• Equal-opportunity employment and skill development
• No child labor or discriminatory hiring

We align our operations with the UN Sustainable Development Goals (SDGs), particularly in ensuring access to affordable, quality healthcare worldwide.

Why Choose BluepillExpress for Secnidazole Manufacturing?

• WHO-GMP certified and ISO-compliant facilities
• Global export experience and regulatory expertise
• Customizable formulations and packaging
• Competitive pricing and flexible MOQs
• Full documentation and registration support
• Timely production and secure international shipping
• Ethical, transparent, and partnership-oriented service

Whether you’re expanding your product portfolio or bidding for large-scale health tenders, BluepillExpress is your ideal manufacturing ally.

Conclusion

Secnidazole is a high-efficacy antiprotozoal with proven clinical utility across a variety of infections. Its single-dose treatment capability makes it especially attractive for mass therapy campaigns, public health initiatives, and private retail markets.

BluepillExpress stands ready to help you manufacture and market Secnidazole under your brand, delivering not just a product but a complete turnkey solution with quality, compliance, and value at the core.